Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
%
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Discount | Price |
---|---|---|---|---|---|---|---|---|
AG-40T-0011-C010 | 10 µg | - |
3 - 9 business days* |
10 %
|
319.00€
287.10€ |
Human full-length PARP-1 [ARTD1] is fused to a MYC and His-tag. Liquid. In 50mM TRIS-HCl, pH 7.5,... more
Product information "PARP-1 [ARTD1] (human) (rec.) (His) (high purity)"
Human full-length PARP-1 [ARTD1] is fused to a MYC and His-tag. Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride and 50mM imidazole, 0.2% NP-40 and 10% glycerol. PARP-1 (ARTD1) is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. PARP-1 positively regulates the transcription of MTUS1 and negatively regulates the transcription of MTUS2/TIP150. It forms a complex with EEF1A1 and TXK that acts as a T-helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.
Keywords: | ADPRT, ARTD1, PARP1, PARP-1, ADPRT 1, EC=2.4.2.30, Poly[ADP-ribose] synthase 1, Poly [ADP-ribose] polymerase 1, NAD(+) ADP-ribosyltransferase 1, ADP-ribosyltransferase diphtheria toxin-like 1 |
Supplier: | AdipoGen Life Sciences |
Supplier-Nr: | AG-40T-0011 |
Properties
Application: | Enzyme assays |
Conjugate: | No |
Host: | Insect cells |
Species reactivity: | human |
Format: | Liquid |
Database Information
KEGG ID : | K24070 | Matching products |
UniProt ID : | P09874 | Matching products |
Gene ID | GeneID 142 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
-10 %
Viewed