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Sulindac
Sulindac

Item number: Cay10004386-1000

Sulindac is a non-steroidal anti-inflammatory drug (NSAID), a COX-2 inhibitor (IC50 = 0.79 µM), and a prodrug form of the COX inhibitor sulindac sulfide (Cay-10004387). It is selective for COX-2 over COX-1 (IC50 = >1,000 µM). It inhibits acetic acid-induced writhing in mice and reduces carrageenan-induced paw edema...
Keywords: 5-fluoro-2-methyl-1Z-[[4-(methylsulfinyl)phenyl]methylene]-1H-indene-3-acetic acid
Application: COX inhibitor
CAS 38194-50-2
MW: 356.4 D
From 19.00€ *
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PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) (ammonium salt)
PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) (ammonium salt)

Item number: Cay10008390-100

The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3, also known as PIP3, is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is...
Keywords: DHPI-3,4,5-P3, Phosphatidylinositol-3,4,5-triphosphate C-6, PIP3C-16,...
Application: Bioactive lipid assays
CAS 799268-62-5
MW: 838.6 D
From 68.00€ *
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