13 products were found matching "AG-40T-0307"!

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Anti-TLR8 (human), clone ABM15F6
Anti-TLR8 (human), clone ABM15F6

Item number: AG-20T-0307-C100

TLR8 (Toll-like Receptor 8) is a member of the TLR (Toll-like receptor) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLR8 is a nucleotide-sensing TLR. TLR8 and TLR7 recognize single-stranded RNA (ssRNA) sequences containing GU-rich or poly-U sequences as their...
Keywords: Anti-TLR8, Anti-CD288, Anti-Toll-like receptor 8
446.00€ * 401.40€ *
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Arginase I (human) (rec.) (highly active)
Arginase I (human) (rec.) (highly active)

Item number: AG-40T-0124-3010

Protein function: Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively, the urea cycle takes place primarily in the liver...
Keywords: ARG1, Arginase-1, Type I arginase, Liver-type arginase
Expressed in: E.coli
Origin: human
270.00€ * From 243.00€ *
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NAD Kinase (M. tuberculosis) (His)
NAD Kinase (M. tuberculosis) (His)

Item number: AG-40T-0107-C050

NAD kinase (Mycobacterium tuberculosis) is fused at the N-terminus to a His-tag. Liquid. In 10mM TRIS at pH 8.0, containing 1mM MgCl2, 0.5mM EDTA, 1mM DTT and 1mM PMSF. NAD kinase catalyzes the transfer of a phosphate group from ATP to NAD+ to generate NADP+, which in its reduced form acts as an electron donor for...
Keywords: ppnK, Rv1695, EC=2.7.1.23, Poly(P)/ATP NAD kinase, Inorganic polyphosphate/ATP-NAD kinase
Application: Enzyme assays
Expressed in: E.coli
Origin: M. tuberculosis
MW: 33.0 kD
418.00€ * 376.20€ *
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SuperKillerTRAIL(TM), Soluble (mouse, rec.)
SuperKillerTRAIL(TM), Soluble (mouse, rec.)

Item number: AG-40T-0004-3020

(3 x 20µg). The extracellular domain of mouse TRAIL (amino acids 99-291) is fused at the N-terminus to a His-tag and a linker peptide. The active multimeric conformation is stabilized by an inserted mutation allowing an additional CC-bridge. Induces apoptosis at concentrations of >10ng/ml as tested on human tumor...
Keywords: TRAIL, Apo-2L, TNFSF10, CD253
Application: Bioassays
Expressed in: E.coli
Origin: mouse
385.00€ * From 346.50€ *
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SuperKillerTRAIL(TM), Soluble (human, rec.)
SuperKillerTRAIL(TM), Soluble (human, rec.)

Item number: AG-40T-0002-3020

(3 x 20µg). The extracellular domain of human TRAIL (amino acids 95-281) is fused at the N-terminus to a His-tag and a linker peptide. The active multimeric conformation is stabilized by an inserted mutation allowing an additional CC-bridge. Induces apoptosis at concentrations of >1ng/ml. Note: Does not require a...
Keywords: TRAIL, Apo-2L, TNFSF10, CD253
Application: Bioassays
Expressed in: E.coli
Origin: human
374.00€ * From 336.60€ *
Review
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KillerTRAIL(TM), Soluble (human, rec.)
KillerTRAIL(TM), Soluble (human, rec.)

Item number: AG-40T-0001-3050

(3 x 50µg). The extracellular domain of human TRAIL (amino acids 95-281) is fused at the N-terminus to a His-tag and a linker peptide. Induces apoptosis in a concentration range of 10-100ng/ml. Note: Does not require a cross-linking enhancer for its potent biological activity. ED50: 20ng/ml (BJAB cells). For cell...
Keywords: TRAIL, Apo-2L, TNFSF10, CD253
Application: Bioassays
Expressed in: E.coli
Origin: human, mouse
451.00€ * From 405.90€ *
Review
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GCN5 (human) (rec.) (His) (highly active)
GCN5 (human) (rec.) (His) (highly active)

Item number: AG-40T-0017-C002

Human GCN5 is fused to a His-tag. Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 0.2% NP-40, 50mM imidazole and 10% glycerol. GCN5 functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription...
Keywords: GCN5, KAT2A, HsGCN5, STAF97, EC=2.3.1.48, Lysine acetyltransferase 2A, Histone acetyltransferase GCN5, Histone...
Application: HAT enzyme assays
Expressed in: Insect cells
Origin: human
242.00€ * 217.80€ *
Review
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PLGF (human) (rec.)
PLGF (human) (rec.)

Item number: AG-40T-0047-C005

Human PLGF (131aa). Lyophilized. Human placenta growth factor-1 (PLGF-1, PLGF) binds to the receptor FLT1/VEGFR-1. It acts as a potent chemoattractant for monocytes and only as a very weak mitogen for some endothelial cell types. The physiological function in vivo is still controversial. In several reports it was...
Keywords: PGF, PGFL, PlGF, Placenta growth factor
Application: Bioassay
Expressed in: Insect cells
Origin: human
MW: 34 kD
270.00€ * From 243.00€ *
Review
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PARP-3 [ARTD3] (human) (rec.) (His) (high purity)
PARP-3 [ARTD3] (human) (rec.) (His) (high purity)

Item number: AG-40T-0013-C010

Human full-length PARP-3 [ARTD3] is fused to a HA-tag and a His-tag. Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride and 50mM imidazole, 0.2% NP-40 and 10% glycerol. PARP-3 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of...
Keywords: IRT1, ARTD3, PARP3, ADPRT3, PARP-3, hPARP-3, ADPRT-3, pADPRT-3, EC=2.4.2.30, Poly[ADP-ribose] synthase 3, Poly...
Application: Enzyme assays
Expressed in: Insect cells
Origin: human
319.00€ * 287.10€ *
Review
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VEGF 165 (human) (rec.)
VEGF 165 (human) (rec.)

Item number: AG-40T-0043-C005

Human VEGF 165 (165aa). Lyophilized. Human vascular endothelial growth factor (VEGF 165) is produced as a homodimer. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. VEGF 165 is a specific mitogen for vascular endothelial cells and a strong angiogenic factor in vivo. In addition to...
Keywords: VPF, VEGF, VEGFA, VEGF-A, Vascular permeability factor, Vascular endothelial growth factor A
Application: Cell culture
Expressed in: E.coli
Origin: human
MW: 38.2 kD
182.00€ * From 163.80€ *
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Zmp1 (M. tuberculosis) (rec.) (His)
Zmp1 (M. tuberculosis) (rec.) (His)

Item number: AG-40T-0103-C050

Prefered cleavage sequence is PxxF. Full-length Zmp1 (Mycobacterium tuberculosis) is fused at the N-terminus to a His-tag. Liquid. In 10mM TRIS-HCl, pH 8.0. M13 endopeptidases are single-pass, transmembrane zinc-metallopeptidases responsible in human for the regulation of the biological activity of many hormones and...
Keywords: zmp1, MT0208, Probable zinc metalloprotease Zmp1, Endopeptidase, peptidase family M13
Application: Enzyme assays
Expressed in: E.coli
Origin: M. tuberculosis
MW: 73.9 kD
495.00€ * 445.50€ *
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NMNAT3 (human) (rec.) (His) (highly active)
NMNAT3 (human) (rec.) (His) (highly active)

Item number: AG-40T-0093-C010

Human full-length NMNAT3 (aa 1-252) is fused at the N-terminus to a His-tag. Liquid. In 50mM TRIS-HCl, pH 8.0, containing 300mM sodium chloride, 1mM DTT and 10% glycerol. Mitochondrial NMNAT isoform. Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form of...
Keywords: PNAT-3, NMNAT3, FKSG76, EC=2.7.7.1, EC=2.7.7.18, NMN adenylyltransferase 3, NaMN adenylyltransferase 3, Pyridine...
Application: Enzyme assays
Expressed in: E.coli
Origin: human
MW: 27 kD
242.00€ * From 217.80€ *
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