- Search results for AG-CN2-0050
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34 products were found matching "AG-CN2-0050"!
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Item number: AG-CN2-0050-M050
Hypolipemic cell permeable and irreversible pancreatic, gastric and carboxylester lipase inhibitor. Anti-obesity and antihypercholesterolemic compound. Antitumor compound by inhibition of the thioesterase domain of fatty acid synthase (FASN). Anti-proliferative. Causes cell cycle arrest at G1 phase. Apoptosis...
Keywords: | Tetrahydrolipstatin, Xenical, Alli, Ro-18-0647 |
Application: | Carboxylester Lipase Inhibitor |
Host: | Synthetic |
CAS | 96829-58-2 |
MW: | 495,7 D |
From 33.00€
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Item number: AG-CN2-0500-M001
Off-white solid to pale yellow solid. Soluble in DMSO, dichloromethane, acetone or 100% ethanol. Poorly soluble in water. Anti-inflammatory compound. Potent dual inhibitor of pro-inflammatory transcription factors and inflammatory enzymes, Inhibitor of NFkappaB activation, Potent inhibitor of inducible microsomal...
Keywords: | Homoarenol, 3-[[3-Acetyl-2,4,6-trihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]methyl]-6-ethyl-4-hydroxy-5-methyl-2H-pyran-2-one |
Application: | Antiinflammatory compound, ALOX5 inhibitor |
CAS | 32274-52-5 |
MW: | 402,4 D |
154.00€
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Item number: AG-CN2-0089-M050
Isolated from Coleus forskohlii. Potent, cell permeable adenylyl cyclase activator. Increases intracellular cAMP levels. Widely used tool to investigate cAMP as a second messenger. Inotropic and antihypertensive. Smooth muscle relaxant/vasodilator. Glucose transporter inhibitor. Platelet aggregation inhibitor....
Keywords: | Boforsin, Colforsin, Coleonol, NSC 357088, NSC 375489 |
Application: | Cell permeable adenylate cyclase activator |
CAS | 66575-29-9 |
MW: | 410,5 D |
From 22.00€
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Item number: AG-CN2-0037-C050
Isolated from Jaspis splendens. Cell permeable, non-fluorescent F-actin probe. Potent inducer of actin polymerization and stabilization. Competes with phallotoxins for actin binding. Antifungal and antiparasitic compound. Antiproliferative and anticancer compound. Apoptosis enhancer/inducer. Tool used for...
Keywords: | Jaspamide, NSC 613009 |
Application: | Actin polymerization inducer |
CAS | 102396-24-7 |
MW: | 709,7 D |
From 253.00€
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Item number: AG-CN2-0046-M250
Antibiotic Diabetogenic. Diabetes inducer. Induces diabetes mellitus in animal models through its toxic effects on pancreatic beta-cells Mutagenic. Potent alkylating agent. Potent DNA methylating agent Nitric oxide (NO) donor. Vasorelaxant. Cytotoxic to cells that express GLUT2 glucose transporter....
Keywords: | 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose, Streptozocin, STZ, NSC 85998, Antibiotic U9889, Zanosar |
Application: | Alkylating agent |
Host: | Synthetic |
CAS | 18883-66-4 |
MW: | 265,2 D |
From 33.00€
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Item number: AG-CN2-0533-M050
Isolated from venenum bufonis. Soluble in DMSO (5mg/ml), ethanol (15mg/ml) or DMF (20mg/ml). Bufalin is a cardiotonic steroid with anaesthetic, blood pressure stimulatory and respiratory activities. It is a potent Na+/K+-ATPase transporter inhibitor (Kd = 42, 45, and 40nM for the alpha1, alpha2, and alpha3...
Keywords: | (3beta,5beta)-3,14-Dihydroxy-bufa-20,22-dienolide, NSC 89595, BRN 5141601 |
Application: | Cardiotonic steroid, Potent Na+/K+-ATPase transporter inhibitor |
CAS | 465-21-4 |
MW: | 386.5 D |
From 77.00€
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Item number: AG-CN2-0463-M050
White solid. Soluble in DMSO, DMF or MeOH. Insoluble in water Potent anticancer compound, Cell permeable potent DNA topoisomerase I (Topo I) complex inhibitor, Potent apoptosis inducer, Binds reversibly to the DNA topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and...
Keywords: | CPT, NSC 94600 |
Application: | Anticancer compound, Cell-permeable TOP1 inhibitor |
CAS | 7689-03-4 |
MW: | 348,4 D |
From 29.00€
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Item number: AG-CN2-0427-M050
White to off-white solid. Soluble in DMSO, slightly soluble in ethanol. Insoluble in water. Cell-permeable, reversible, substrate competitive tyrosine kinase inhibitor (including EGFR phosphorylation), implicated in almost all cell growth and proliferation signal cascades, Inhibitor of mammalian DNA topoisomerase...
Keywords: | NSC 36586, Baichanin A, Differenol A, 4',5,7-Trihydroxyisoflavone, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
Application: | Tyrosine kinase inhibitor |
CAS | 446-72-0 |
MW: | 270,2 D |
From 28.00€
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Item number: AG-CN2-0024-M050
Isolated from Piper longum roots. Cytotoxic against tumor cell lines. Induces necrosis and apoptosis in cancer cells. Shows anti-platelet aggregation activity possibly by inhibition of cyclooxgenase activity and a decrease in thromboxane A2 formation. Shows significant anxiolytic and antidepressant activities....
Keywords: | Piplartine, 5,6-Dihydro-1-(1-oxo-3-[3,4,5-trimethoxyphenyl]-trans-2-propenyl)-2[1H]-pyridinone |
Application: | Apoptosis inducer |
CAS | 20069-09-4 |
MW: | 317,3 D |
From 33.00€
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Item number: AG-CN2-0036-M050
Potent phenolic antioxidant found in grapes and red wine. Eicosanoid synthesis and platelet aggregation inhibitor. Estrogen receptor agonist. Chemopreventive. Specific inhibitor of cyclooxygenase-1. Anti-inflammatory. Ribonucleotide reductase and DNA synthesis. Arrests cell cycle at S/G2 phase. Anticancer and...
Keywords: | trans-3,4,5-Trihydroxystilbene, trans-Resveratrol, (E)-Resveratrol, 3,4,5-Stilbenetriol |
Application: | Antioxidant, Adipogenesis inhibitor, Chemopreventive |
CAS | 501-36-0 |
MW: | 228,2 D |
From 33.00€
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Item number: AG-CN2-0092-C250
Isolated from Penicillium sp. Soluble in methanol, ethanol, acetone or DMSO. Mycotoxin. Potent and selective competitive protein phosphatase 2A (PP2A) inhibitor. Does not inhibit PP1, PP2B, PTP1B, ALP and CIP. Antitumor agent. Antimetastatic.
Keywords: | BRN 1633008, HSDB 3532 |
Application: | PP2A inhibitor |
CAS | 22467-31-8 |
MW: | 520,2 D |
From 363.00€
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Item number: AG-CN2-0331-M050
Semisynthetic. Red powder. Soluble in DMSO, aqueous acetonitrile or ethanol. Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria, and are therefore used in research of tuberculosis, leprosy and mycobacterium avium complex (MAC) infections.
Keywords: | Rifamycin AMP/DA, 25-desacetyl AF-AMP, Deacetylrifampicin, Desacetylrifampin, 25-O-Deacetylrifampicin, 25-O-Desacetylrifampin |
Application: | Antibiotic, Bacterial DNA-dependent RNA polymerase inhibitor |
CAS | 16783-99-6 |
MW: | 780.9 D |
From 138.00€
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