CD45 is a receptor-tyrosine phosphatase required for antigen-induced signaling in T-cells and B-cells, its substrates are unknown. Interestingly, it associates with several Src-family tyrosine kinases, which are inhibited by tyrosine phosphorylation in their c-termini, suggesting a mechanism for signaling by CD45....

Applications:, Suitable for use in Immunoelectrophoresis, RID, ELISA, Western Blot and Inhibition. Other applications have not been tested. , Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at...

Nuclease P1 (Nuclease 5'-Nucleotidehydrolase, 3'-Phosphohydrolase) hydrolyzes both 3'-5'- phosphodiester bonds in RNA and heat denatured DNA and 3'-phosphomonoester bonds in mono- and oligonucleotides terminated by 3'-phosphate without base specificity. The enzyme does not attack double-stranded nucleic acids,...