Mouse IL-33 (amino acids 109-266) is fused at the C-terminus to a His-tag. Activates human ST2-dependent NF-kappaB pathway. Liquid. 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. Interleukin-33 (IL-33, HF-NEV, IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell...

Signal peptide and extracellular domain of human DLL1 (amino acids 1-545) are fused at the C-terminus to a FLAG(R)-tag. Inhibits adipogenesis of mesenchymal stem cells. Liquid. 0.2µm-filtered solution in PBS. The Notch ligand delta-like protein 1 (DLL1) is essential for postnatal arteriogenesis and contributes to...

Human ANGPTL7 (amino acids 1-346) is fused at the C-terminus to a FLAG(R)-tag. Activates ERK phosphorylation in THP-1 cells. Liquid. 0.2µm-filtered solution in PBS. ANGPTL7 (Angiopoietin-like protein 7) is expressed in various tissues and regulates angiogenesis. Human ANGPTL7 was characterized as a potent target...

Signal peptide and human progranulin (aa 1-593) are fused at the C-terminus to a FLAG(R)-tag. Activates ERK phosphorylation in THP-1 and MCF10A cells and induces cell migration of THP-1 monocytic leukemia cells. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such...

SIGIRR acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through a TIR-TIR domain interaction with TLR4. Protein function: Acts as a negative regulator of the Toll-like and IL-1R...