7 products were found matching "AG-40A-0063-C010"!

Mouse IL-33 (amino acids 109-266) is fused at the C-terminus to a His-tag. Activates human ST2-dependent NF-kappaB pathway. Liquid. 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. Interleukin-33 (IL-33, HF-NEV, IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell...

Signal peptide and extracellular domain of human DLL1 (amino acids 1-545) are fused at the C-terminus to a FLAG(R)-tag. Inhibits adipogenesis of mesenchymal stem cells. Liquid. 0.2µm-filtered solution in PBS. The Notch ligand delta-like protein 1 (DLL1) is essential for postnatal arteriogenesis and contributes to...

Human ANGPTL7 (amino acids 1-346) is fused at the C-terminus to a FLAG(R)-tag. Activates ERK phosphorylation in THP-1 cells. Liquid. 0.2µm-filtered solution in PBS. ANGPTL7 (Angiopoietin-like protein 7) is expressed in various tissues and regulates angiogenesis. Human ANGPTL7 was characterized as a potent target...

Signal peptide and human progranulin (aa 1-593) are fused at the C-terminus to a FLAG(R)-tag. Activates ERK phosphorylation in THP-1 and MCF10A cells and induces cell migration of THP-1 monocytic leukemia cells. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such...

Vaspin (Visceral adipose tissue-derived serpin, Serpin A12), a serine protease inhibitor (serpin), is an insulin-sensitizing adipocytokine that has been isolated from both visceral and subcutaneous white adipose tissue. Based on recent findings, vaspin is suggested to regulate immune responses and inflammation and...

Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor...

SIGIRR acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through a TIR-TIR domain interaction with TLR4. Protein function: Acts as a negative regulator of the Toll-like and IL-1R...