9 products were found matching "AG-CN2-0062-M001"!

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Staurosporine
Staurosporine

Item number: AG-CN2-0022-M001

Isolated from Streptomyces spiralis. Antibiotic. Antifungal and anti-yeast activity. Inhibits platelet aggregation induced by collagen or ADP. Has no effect on thrombin-induced platelet aggregation. Potent, cell permeable, reversible, ATP-competitive and broad spectrum inhibitor of protein kinases. Inhibits protein...
Keywords: Antibiotic AM2282, Antibiotic 230, CCRIS 3272
Application: Protein kinase inhibitor, Apoptosis inducer
CAS 62996-74-1
MW: 466,5 D
50.00€ * From 45.00€ *
Review
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Ingenol-3-angelate
Ingenol-3-angelate

Item number: AG-CN2-0012-M001

Specific protein kinase C (PKC) activator, Selective activator of PKC isoforms, like PKCtheta in T cells, Antiproliferative and proapoptotic (necrotic), Immunostimulant, Chemotherapeutic, Anticancer compound, Efficacious agent against actinic kerastosis, Antileukemic. Isolated from Euphorbia peplus L.
Keywords: PEP005, I3A
Application: Protein kinase C (PKC) activator
CAS 75567-37-2
MW: 430,5 D
132.00€ * From 118.80€ *
Review
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4alpha-PMA
4alpha-PMA

Item number: AG-CN2-0082-M001

Semi-synthetic. Negative control for phorbol ester activation of protein kinase C and studies with PMA (AG-CN2-0010). Might be a reasonable PKC-independent TRPV4 channels agonist.
Keywords: 4alpha-PMA, 4alpha-TPA, 4alpha-12-O-Tetradecanoylphorbol 13-acetate
Application: TRPV4 channels agonist
CAS 63597-44-4
MW: 616,8 D
72.00€ * 64.80€ *
Review
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(3S,6R)-Lateritin
(3S,6R)-Lateritin

Item number: AG-CN2-0042-M001

N-methylated peptide that is structurally equivalent to a monomer of beauvericin (Prod. No. AG-CN2-0043). Acyl-CoA:cholesterol acyltransferase inhibitor. Platelet aggregation inhibitor. Antimicrobial. Note: The (3R,6R)-stereoisomer was shown to have anti-cancer and apoptosis inducing activity.
Keywords: (3S,6R)-Bassiatin, Antibiotic PI290
Application: Apoptosis inducer
Host: Gibberella sp.
CAS 65454-13-9
MW: 261,3 kD
165.00€ * 148.50€ *
Review
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White Line Inducing Principle [WLIP]
White Line Inducing Principle [WLIP]

Item number: AG-CN2-0069-M001

Lipodepsipeptide (LDP). Used as a diagnostic tool to identify tolaasin-producing bacteria pathogenic to mushrooms and responsible for brown blotch disease. Has haemolytic activity. Permeabilizes lipid vesicles and is involved in mushroom tissue alterations by forming transmembrane pores. Antimicrobial....
Keywords: WLIP
Application: Metabolic studies
Host: Pseudomonas sp
CAS 135096-89-8
MW: 1126,4 D
105.00€ * 94.50€ *
Review
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Sauchinone
Sauchinone

Item number: AG-CN2-0032-M001

Isolated from Saururus chinensis. Hepatoprotective antioxidant. Anti-inflammatory. Suppresses NF-kB p65 activity. Neuroprotective. Apoptosis inhibitor. Bone resorption/osteoclastogenesis inhibitor. Reduces ROS formation. Antiseptic. AMP-activated kinase (AMPK) activator. Akt phosphorylation inhibitor.
Keywords: 1'-Epimer dihydrocarpanone
Application: NF-kB p65 activity suppressor
CAS 177931-17-8
MW: 356,4 D
33.00€ * From 29.70€ *
Review
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Aspergillin PZ
Aspergillin PZ

Item number: AG-CN2-0162-M001

Isolated from Aspergillus sp. Antibiotic. Inducer of morphological deformation of the conidia of Pyricularia oryzae.
Application: Antibiotic
CAS 483305-08-4
MW: 401,6 D
165.00€ * From 148.50€ *
Review
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Okadaic acid, sodium salt (high purity)
Okadaic acid, sodium salt (high purity)

Item number: AG-CN2-0062-C025

Non-phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-1nM), PP1 (IC50=3-15nM), PP2B (IC50=>1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful tool for studying cellular processes that are regulated by...
Keywords: Halochondrine A, CCRIS 3329, HSDB 7243, 9,10-Deepithio-9,10-didehydroacanthifolicin
Application: Ser/Thr phosphatase inhibitor
CAS 209266-80-8
MW: 827 D
99.00€ * 89.10€ *
Review
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Skyrin
Skyrin

Item number: AG-CN2-0001-M001

Non-peptidic anti-diabetic agent, Receptor-selective glucagon antagonist, Free radical species (.OH, R.) and singlet oxygen (1O2) scavenger, Mycotoxin, Cytotoxic, Antioxidant. Isolated from fungus Talaromyces sp.
Keywords: Rhodophyscin, Endothianin
Application: Antioxidant, Glucagon antagonist
CAS 602-06-2
MW: 538,5 D
176.00€ * 158.40€ *
Review