4 products were found matching "AG-CN2-0060-C025"!
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Okadaic acid, sodium salt (high purity)
Item number: AG-CN2-0062-C025
Non-phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-1nM), PP1 (IC50=3-15nM), PP2B (IC50=>1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful tool for studying cellular processes that are regulated by...
| Keywords: | Halochondrine A, CCRIS 3329, HSDB 7243, 9,10-Deepithio-9,10-didehydroacanthifolicin |
| Application: | Ser/Thr phosphatase inhibitor |
| CAS | 209266-80-8 |
| MW: | 827 D |
99.00€
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Nigericin, sodium salt
Item number: AG-CN2-0020-M025
Isolated from Streptomyces hygroscopicus. Antibiotic. High affinity ionophore for monovalent cations such as H, K, Na, Pb2. Shows antibacterial (Gram-positive), antifungal, antitumor and antiviral activity. Disrupts membrane potential and Golgi apparatus in mitochondria. NLRP3/NALP3 activator. Signals through...
| Keywords: | Antibiotic K 178, Helexin C, Polyetherin A, BRN 1696755, Azalomycin M, Antibiotic X-464 |
| Application: | Ionophore |
| CAS | 28643-80-3 |
From 66.00€
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Rapamycin
Item number: AG-CN2-0025-C100
Isolated from Streptomyces hygroscopicus. Antibiotic. Antibacterial and antifungal properties. Forms a complex with FKBP12 and inhibits the molecular target of rapamycin (mTOR). Inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T and B cells. Potent immunosuppressant used as an...
| Keywords: | Sirolimus, Rapamune, NSC 226080, Antibiotic AY-22989, WY-090217, RAPA, SILA 9268A, CCRIS 9024 |
| Application: | mTOR inhibitor, Immunsuppressant, Apoptosis inducer |
| CAS | 53123-88-9 |
| MW: | 914,2 D |
From 28.00€
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Colistin sulfate (USP Grade)
Item number: AG-CN2-0065-G001
Very potent polymyxin antibiotic - Has only one amino acid difference compared to polymyxin B - Antimicrobial - Targets the lipopolysaccharide (LPS) of the outer membrane of Gram-negative bacteria. Competitively displaces divalent cations (Ca2 and Mg2) from the negatively-charged phosphate groups LPS, causing...
| Keywords: | Polymyxin E, Belcomycin, Colimycin |
| Application: | Antibiotic |
| Host: | Bacillus polymyxa |
| CAS | 1264-72-8 |
From 39.00€
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