12 products were found matching "AG-CN2-0060"!

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(-)-Epigallocatechin gallate
(-)-Epigallocatechin gallate

Item number: AG-CN2-0063-M100

Potent anticancer compound - Anti-angiogenic. VEGF, VE-cadherin phosphorylation, matrix metalloproteinase and urokinase-plasminogen activator (uPA) inhibitor - Anti-inflammatory. NF-kappaB inhibitor. Modulates chronic inflammatory diseases, such as type 2 diabetes, rheumatoid arthritis, inflammatory bowel disease -...
Keywords: Epigallocatechin-3-gallate, CCRIS 3729, Teavigo, NVP-XAA 723
Application: NF-kappaB inhibitor
Host: green tea
CAS 989-51-5
MW: 458,4 D
From 28.00€ *
Review
10Z-Hymenialdisine
10Z-Hymenialdisine

Item number: AG-CN2-0067-C500

Insecticidal and cytotoxic - Potent NF-kappaB inhibitor. Inhibits various pro-inflammatory cytokines such as IL-1, IL-2, IL-6, IL-8, TNF-alpha and nitric oxide (NO) in a variety of cell lines - ATP-competitive kinase inhibitor. Inhibits DNA damage checkpoint at G2, cyclin-dependent kinases CDK1/cyclin B, CDK2/cyclin...
Keywords: Hymenialdisine, 4-(2-Amino-4-oxo-2-imidazolidin-5-ylidene)-2-bromo-4,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8-one
Application: NF-kappaB Inhibitor
Host: Axinella carteri
CAS 82005-12-7
MW: 324,1 D
242.00€ *
Review
Debromohymenialdisine
Debromohymenialdisine

Item number: AG-CN2-0068-C100

Protein kinase C (PKC) inhibitor. Inhibits the ATP binding site. Cytotoxic and insecticidal. G2 DNA damage checkpoint inhibitor. Check point kinases 1 (Chk1) and 2 (Chk2) inhibitor. Does not inhibit ataxia-telangiectasia mutated (ATM) or ATM-Rad3-related proteins. MAP kinase kinase 1 (MEK-1) inhibitor....
Keywords: DBH, DBHA-SKF, SKF 108753
Application: PKC Inhibitor
Host: Axinella carteri
CAS 75593-17-8
MW: 245,2 D
143.00€ *
Review
Colistin sulfate (USP Grade)
Colistin sulfate (USP Grade)

Item number: AG-CN2-0065-M100

Very potent polymyxin antibiotic - Has only one amino acid difference compared to polymyxin B - Antimicrobial - Targets the lipopolysaccharide (LPS) of the outer membrane of Gram-negative bacteria. Competitively displaces divalent cations (Ca2 and Mg2) from the negatively-charged phosphate groups LPS, causing...
Keywords: Polymyxin E, Belcomycin, Colimycin
Application: Antibiotic
Host: Bacillus polymyxa
CAS 1264-72-8
From 39.00€ *
Review
Gentamicin sulfate (USP Grade)
Gentamicin sulfate (USP Grade)

Item number: AG-CN2-0066-G001

Aminoglycoside antibiotic - Protein synthesis inhibitor. Causes codon misreading by binding to the 30S ribosomal subunit, blocking the translocation of peptidyl-tRNA from the acceptor site to the donor site - Antibacterial against Gram-negative aerobic bacteria, Gram-positive bacteria and mycoplasmas - Used as a...
Keywords: Apogen, Garamycin, Gentiomycin C, Refobacin, NSC-82261
Application: Antibiotic
Host: Micromonospora sp
CAS 1405-41-0
From 39.00€ *
Review
Wogonin
Wogonin

Item number: AG-CN2-0064-M005

Anti-inflammatory. Increases nitric oxide (NO) production - Inhibits PGE2, cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS, NOS II) - Antioxidant - Anti-viral. Shows anti-hepatitis B virus activity - MCP-1 inhibitor - Shows anxiolytic effect through modulation of the GABA(A) receptor complex -...
Keywords: WOG, 5,7-Dihydroxy-8-methoxyflavone, BRN 0287152, Norwogonin 8-methyl ether
Application: Antioxidant
Host: Laburnum anagyroides
CAS 485-35-8
MW: 190,2 D
From 77.00€ *
Review
Okadaic acid, sodium salt (high purity)
Okadaic acid, sodium salt (high purity)

Item number: AG-CN2-0062-C025

Non-phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-1nM), PP1 (IC50=3-15nM), PP2B (IC50=>1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful tool for studying cellular processes that are regulated by...
Keywords: Halochondrine A, CCRIS 3329, HSDB 7243, 9,10-Deepithio-9,10-didehydroacanthifolicin
Application: Ser/Thr phosphatase inhibitor
CAS 209266-80-8
MW: 827 D
99.00€ *
Review
White Line Inducing Principle [WLIP]
White Line Inducing Principle [WLIP]

Item number: AG-CN2-0069-M001

Lipodepsipeptide (LDP). Used as a diagnostic tool to identify tolaasin-producing bacteria pathogenic to mushrooms and responsible for brown blotch disease. Has haemolytic activity. Permeabilizes lipid vesicles and is involved in mushroom tissue alterations by forming transmembrane pores. Antimicrobial....
Keywords: WLIP
Application: Metabolic studies
Host: Pseudomonas sp
CAS 135096-89-8
MW: 1126,4 D
105.00€ *
Review
Streptozotocin
Streptozotocin

Item number: AG-CN2-0046-M250

Antibiotic Diabetogenic. Diabetes inducer. Induces diabetes mellitus in animal models through its toxic effects on pancreatic beta-cells Mutagenic. Potent alkylating agent. Potent DNA methylating agent Nitric oxide (NO) donor. Vasorelaxant. Cytotoxic to cells that express GLUT2 glucose transporter....
Keywords: 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose, Streptozocin, STZ, NSC 85998, Antibiotic U9889, Zanosar
Application: Alkylating agent
Host: Synthetic
CAS 18883-66-4
MW: 265,2 D
From 33.00€ *
Review
Pyripyropene A
Pyripyropene A

Item number: AG-CN2-0106-C250

Antibiotic, highly specific inhibitor of acyl-coenzyme A:cholesterol acetyltransferase 2 (ACAT2), anti-angiogenic, antiatherogenic and antiatherosclerotic agent. Shows cholesterol-lowering and atheroprotective activities
Keywords: ()-Pyripyropene A, PPPA, FO 1289A
Application: ACAT2 inhibitor
CAS 147444-03-9
MW: 583,2 D
From 154.00€ *
Review
Celastrol
Celastrol

Item number: AG-CN2-0460-M005

Red solid. Soluble in DMSO, ethanol or dimethylformamide. Insoluble in water. Anti-obesity agent. Potent leptin sensitizer, Antioxidant, Potent lipid peroxidation inhibitor, NADPH oxidases (NOX1, 2, 4 and 5) inhibitor, Anti-inflammatory. NF-kappaB inhibitor, HSP90 inhibitor and HSP70 inducer, Anticancer agent....
Keywords: Tripterine, NSC 70931
Application: Antiobesity agent, 20S proteasome chymotrypsin-like activity inhibitor
CAS 34157-83-0
MW: 450,6 D
From 72.00€ *
Review
Thailandolide B
Thailandolide B

Item number: AG-CN2-0160-M001

Isolated from Penicillium sp. Antibiotic. Stereoisomer of chrodrimanin B, which is an insecticidal compound.
Application: Antibiotic
CAS 944726-62-9
MW: 484,6 D
209.00€ *
Review