10 products were found matching "AG-CN2-0058-M001"!

Statin compound, potent competitive HMG-CoA reductase inhibitor, anti-hypercholesterolemic agent, Cholesterol/isoprenoid biosynthesis inhibitor. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids, inhibits the isoprenylation of Ras and Rho family GTPases, causes...

Non-phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-1nM), PP1 (IC50=3-15nM), PP2B (IC50= >1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful tool for studying cellular processes that are regulated by...

Antibacterial, weak antagonist of human endothelin receptor A (ETA) and B (ETB), Cholesteryl ester transfer protein (CETP) activity inhibitor, Grb2-Shc binding inhibitor, potent aldose reductase inhibitor, potent reversible, non-competitive soybean lipoxygenase-1 (LOX-1) inhibitor, antioxidant. Free radical...

White to off-white solid. Soluble in dry DMSO, 100% ethanol or methanol. Insoluble in water. Anticancer compound, Farnesyltransferase inhibitor, Potent anti-inflammatory agent, NF-kappaB inhibitor, Inflammasome inhibitor, Antiatherogenic. Prevents the accumulation of lipid containing plaques in arteries.

A steroidal alkaloid isolated from the desert plant Veratrum californicum with both teratogenic and antitumor activities. It inhibits hedgehog/smoothened signaling.

Key constituent of St, John's wort, Shows properties of potential pharmacological interest, including anti-bacterial , anti-malarial , anti-inflammatory , anti-cancer and anti-angiogenic effects, Anti-depressant and anxiolytic compound, Specific activator of TRPC6 channels, Inhibits the re-uptake of...

Isolated from Streptomyces sp. Antibiotic. Antimycoplasma. Antifungal compound. Anti-malarial agent. Ras-competitive non-CAAX mimetic type farnesyltransferase (FTase) inhibitor. Potential anticancer compound. Inducer of antiproliferative effects in tumor cell lines. Selective DNA (cytosine-5)-methyltransferase 3B...

Semi-synthetic. Soluble in acetic acid, ethanol, methanol or DMSO. Insoluble in water. A member of the ecdysteroid family. Ecdysone receptor (EcR) agonist. Analog of ecdysone with similar properties to muristerone A. Functional, reliable and economical substitute for muristerone A as an inducer for the...

Isolated from Penicillium janthinellum. Protein transport from ER to Golgi inhibitor. ADP-ribosylation factor (Arf) inhibitor. Cytotoxic. Antibiotic. Antiviral. Apoptosis inducer. Antitumor compound. Intracellular collagen degradation inhibitor.

Non-peptidic anti-diabetic agent, Receptor-selective glucagon antagonist, Free radical species (.OH, R.) and singlet oxygen (1O2) scavenger, Mycotoxin, Cytotoxic, Antioxidant. Isolated from fungus Talaromyces sp.