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Efavirenz
Efavirenz

Item number: Cay14412-50

Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that binds to wild-type and mutant HIV-1 RTs (Kis = 2.93 and 3.85-56.5 nM, respectively). It inhibits wild-type and mutant HIV-1 viral replication in MT-4 human T lymphoid cells (IC95s = 1.5-1,500 nM). Efavirenz also prevents RNA plus-strand...
Keywords: DMP 266, EFV, L-743,726, (4S)-6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
Application: Non-nucleoside reverse transcriptase inhibitor
CAS 154598-52-4
MW: 315.7 D
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