OX40 (human):Fc (human, rec.)

OX40 (human):Fc (human, rec.)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
AG-40B-0014-C050 50 µg -

3 - 9 business days*

204.00€
AG-40B-0014-3050 150 µg (3 x 50 µg) -

3 - 9 business days*

407.00€
 
(3 x 50µg). Human OX40 (amino acids 29-214) is fused at the C-terminus to the Fc portion of human... more
Product information "OX40 (human):Fc (human, rec.)"
(3 x 50µg). Human OX40 (amino acids 29-214) is fused at the C-terminus to the Fc portion of human IgG1. Blocks T cell proliferation induced by CD134L. Lyophilized. Contains PBS. OX40 binds to receptors on T-cells, preventing them from dying and subsequently increasing cytokine production. OX40 has a critical role in the maintenance of an immune response. OX40:Fc was shown to prevent OX40 from reaching the T-cell receptors, thus reducing the T-cell response. Experiments in mice have demonstrated that OX40:Fc can reduce the symptoms associated with the cytokine storm (an immune overreaction) while allowing the immune system to fight off the virus successfully.
Keywords: TNFRSF 4, Tumor necrosis factor receptor superfamily member 4, CD134
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-40B-0014

Properties

Application: Bioassays
Conjugate: No
Host: Human cells
Species reactivity: human, mouse
MW: 70 kD
Format: Lyophilized

Database Information

KEGG ID : K05142 | Matching products
UniProt ID : P43489 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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