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ONX 0912
ONX 0912

Item number: Cay16269-1

ONX 0912 is an orally bioavailable proteasome inhibitor. It potently targets the chymotrypsin-like activity of the 20S proteasome subunits beta5 and LMP7 (IC50s = 36 and 82 nM, respectively). ONX 0912 inhibits the growth of multiple myeloma cells at nanomolar concentrations while not decreasing the viability of...
Keywords: Oprozomib, PR-047,...
Application: EGFR T790M inhibitor
CAS 935888-69-0
MW: 532.6 D
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