3 products were found matching "Cay14522"!

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ONO-AE3-208
ONO-AE3-208

Item number: Cay14522-5

ONO-AE3-208 is an antagonist of the EP4 receptor (Ki = 1.3 nM) which less potently affects EP3, FP, and TP receptors (Kis = 30, 790, and 2,400 nM, respectively) and is without effect on other prostanoid receptors. In wild type mice, it mimics deletion of EP4 by producing severe colitis, with epithelial loss, crypt...
Keywords: 4-cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]-benzenebutanoic acid
Application: EP4 receptor antagonist
CAS 402473-54-5
MW: 404.4 D
From 60.00€ *
Review
Phloretin
Phloretin

Item number: Cay14452-250

Phloretin is a natural phenol which inhibits a variety of transporters. It inhibits the monocarboxylate transporters MCT1 and MCT2 (IC50 = 28 and 14 µM, respectively), restricting the rapid transport of monocarboxylates like lactate and pyruvate across the plasma membrane. Phloretin also blocks the sodium/D-glucose...
Keywords: NSC 407292, RJC 02792, 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone
Application: Monocarboxylate transporter inhibitor
CAS 60-82-2
MW: 274.3 D
From 56.00€ *
Review
5-fluoro PB-22 7-hydroxyisoquinoline isomer
5-fluoro PB-22 7-hydroxyisoquinoline isomer

Item number: Cay14552-5

5-fluoro PB-22 is a synthetic cannabinoid that is an analog of potent 5-fluoropentyl JWH-type cannabimimetics. 5-fluoro PB-22 7-hydroxyisoquinoline isomer differs from 5-fluoro PB-22 by having the quinoline group replaced with an isoquinoline group attached at its seven position. The physiological and...
Keywords: 1-(5-fluoropentyl)-1H-indole-3-carboxylic acid, 7-isoquinolinyl ester
Application: Analytical reference standard, synthetic cannabinoid analog
CAS 2365471-81-2
MW: 376.4 D
From 109.00€ *
Review