- Search results for Cay14070-5
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6 products were found matching "Cay14070-5"!
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Item number: Cay14075-500
Polymyxin B1 isoleucine differs from polymyxin B1 by having isoleucine rather than leucine as a component of the cyclic peptide. Polymyxin B1 isoleucine is comparable to other B polymyxins in its ability to kill P. aeruginosa, A. baumannii, and K. pneumoniae isolates. Its relative pharmacokinetics and nephrotoxicity...
Keywords: | N-((S)-4-amino-1-(((2S,3R)-1-(((S)-4-amino-1-oxo-1-(((3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-12-((S... |
Application: | Antibiotic |
MW: | 1301.6 D |
161.00€
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Item number: Cay14072-500
Porcupine (PORCN) is a membrane bound O-acyltransferase that mediates palmitoylation of Wnt family proteins. This step is required for secretion and biologic activity of Wnt proteins, which have roles in embryonic development and cancer. LGK974 is a potent and specific small molecule inhibitor of PORCN (IC50 = 0.4...
Keywords: | PORCN Inhibitor IV, 2',3-dimethyl-N-[5-(2-pyrazinyl)-2-pyridinyl]-[2,4'-bipyridine]-5-acetamide |
Application: | PORCN inhibitor |
CAS | 1243244-14-5 |
MW: | 396.4 D |
From 50.00€
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Item number: Cay14005-5
Bafilomycin B1 is a bacterial metabolite that has been found in Streptomyces and has diverse biological activities. It inhibits the activity of rat liver lysosomal vacuolar H+-ATPase (V-ATPase) in a concentration-dependent manner. Bafilomycin B1 (10-1,000 nM) induces autophagosome accumulation in MCF-7 cells. It...
Keywords: | Setamycin, 4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-4-oxo-2E-butenoic acid,... |
Application: | V-ATPase inhibitor |
CAS | 88899-56-3 |
MW: | 816 D |
From 56.00€
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Item number: Cay14705-50
Vildagliptin is an inhibitor of dipeptidyl peptidase 4 (DPP-4, Ki = 0.003 µM). It is selective for DPP-4 over DPP-2, DPP-8, and DPP-9 (Kis = >500, 0.81, and 0.095 µM, respectively). Vildagliptin (3 mg/kg) decreases plasma glucose levels and increases plasma insulin levels during an oral glucose challenge in Zucker...
Keywords: | 1-[2-[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2S-pyrrolidinecarbonitrile |
Application: | DPP4 / DPP8 / DPP9 inhibitor |
CAS | 274901-16-5 |
MW: | 303.4 D |
From 39.00€
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Item number: Cay10705-50
(±)9-HpODE is a racemic mixture of the fatty acid hydroperoxide product (9(S)-HpODE) formed from lipoxygenase action on linoleic acid. It shows antimicrobial activity against various fungal and bacterial pathogens and thus may play a role in plant defense. In mammalian species, monocyte-induced oxidization of LDL...
Keywords: | (±)9-hydroperoxy-10E,12Z-octadecadienoic acid |
Application: | Bioactive lipid studies |
CAS | 5502-91-0 |
MW: | 312.4 D |
From 134.00€
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Item number: Cay14078-50
bk-MDEA (hydrochloride) (Cay-9001123, ethylone) is a psychotropic cathinone that has been detected in products marketed as bath salts, plant food, and tablets. 3,4-Methylenedioxy-5-methylethcathinone is an analog of bk-MDEA, differing by the addition of a methyl group at the two position of the benzene ring. The...
Keywords: | 3,4-Methylenedioxy-5-methyl-N-ethyl Cathinone, R-MMC, 2-(ethylamino)-1-(7-methyl-1,3-benzodioxol-5-yl)-1-propanone,... |
Application: | Analytical reference standard, Cathinone bk-MDEA analog |
CAS | 2748289-02-1 |
MW: | 271.7 D |
From 266.00€
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