- Search results for Cay14070-25
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7 products were found matching "Cay14070-25"!
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Item number: Cay14072-5
Porcupine (PORCN) is a membrane bound O-acyltransferase that mediates palmitoylation of Wnt family proteins. This step is required for secretion and biologic activity of Wnt proteins, which have roles in embryonic development and cancer. LGK974 is a potent and specific small molecule inhibitor of PORCN (IC50 = 0.4...
Keywords: | PORCN Inhibitor IV, 2',3-dimethyl-N-[5-(2-pyrazinyl)-2-pyridinyl]-[2,4'-bipyridine]-5-acetamide |
Application: | PORCN inhibitor |
CAS | 1243244-14-5 |
MW: | 396.4 D |
From 50.00€
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Item number: Cay10702-5
Janus-associated kinases (JAKs) are cytoplasmic tyrosine kinases that are required for activating the signaling of certain cytokines and growth factor receptors. Many myeloproliferative diseases have been linked to a mutation in JAK2 where a switch from valine to phenylalanine occurs at the 617 position (V617F). AZD...
Keywords: | 5-chloro-N2-[(1S)-1-(5-fluoro-2-pyrimidinyl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)-2,4-pyrimidinediamine |
Application: | JAK2 inhibitor |
CAS | 935666-88-9 |
MW: | 348.8 D |
From 50.00€
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Item number: Cay14002-5
Alliin is a cysteine sulfoxide constituent of garlic that is converted by alliinase to allicin, which imparts its pungent aroma and flavor. Alliin exhibits anti-cancer, anti-microbial, anti-hypertensive, cardioprotective, and anti-oxidant activities. S-allyl-cysteine is oxidized stereospecifically to (+)-alliin by...
Keywords: | S-Allyl-L-cysteine sulfoxide, [S(S)]-S-2-propen-1-yl-S-oxide-L-cysteine |
Application: | Bioactive cysteine sulfoxide, antioxidant |
CAS | 556-27-4 |
MW: | 177.2 D |
From 52.00€
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Item number: Cay14079-250
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH), a key enzyme in carbohydrate metabolism, reversibly catalyzes the conversion of GAP to 1,3-bisphosphoglycerate and NAD+. Heptelidic acid is a sesquiterpene lactone produced by the fungus T. koningii that was shown to have antibiotic activity against anaerobic...
Keywords: | Avocettin, BRN 5091359, FO-4443, Koningic Acid,... |
Application: | Irreversible GAPDH inhibitor |
CAS | 57710-57-3 |
MW: | 280.3 D |
From 171.00€
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Item number: Cay14020-50
1-(4-Methoxyphenyl)piperazine (hydrochloride) is a piperazine derivative with euphoric, stimulant properties comparable to those produced by amphetamine. It is assumed to have a mixed mechanism of action, with serotonergic and dopamine antagonistic properties in a similar fashion to...
Keywords: | p-MeOPP, para-MeOPP, 1-(p-Methoxyphenyl)piperazine, 1-(para-Methoxyphenyl)piperazine, 4-MeOPP,... |
Application: | Analytical reference standard, Piperazine derivative, Euphoric, Stimulant |
CAS | 38869-47-5 |
MW: | 265.2 D |
From 60.00€
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Item number: Cay14075-500
Polymyxin B1 isoleucine differs from polymyxin B1 by having isoleucine rather than leucine as a component of the cyclic peptide. Polymyxin B1 isoleucine is comparable to other B polymyxins in its ability to kill P. aeruginosa, A. baumannii, and K. pneumoniae isolates. Its relative pharmacokinetics and nephrotoxicity...
Keywords: | N-((S)-4-amino-1-(((2S,3R)-1-(((S)-4-amino-1-oxo-1-(((3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-12-((S... |
Application: | Antibiotic |
MW: | 1301.6 D |
161.00€
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Item number: Cay10004970-25
Cloprostenol is a synthetic derivative of prostaglandin F2alpha that is used in veterinary medicine as a luteolytic agent for the induction of estrus and in the treatment of reproductive disorders in cattle, swine, and horses. (+)-5-trans Cloprostenol is a minor impurity produced in the synthesis of...
Keywords: | (+)-5,6-trans Cloprostenol, (+)-5-trans-16-m-chlorophenoxy tetranor PGF2alpha, (+)-5-trans-16-m-chlorophenoxy tetranor... |
Application: | Bioactive lipid assays |
CAS | 57968-81-7 |
MW: | 424.9 D |
From 114.00€
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