- Search results for Cay14070-10
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15 products were found matching "Cay14070-10"!
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Item number: Cay14010-1
PGE2 is one of the primary COX products of arachidonic acid (Cay-90010) and one of the most widely investigated prostaglandins. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation. The effects of PGE2 are transduced by at least four distinct receptors...
Keywords: | Dinoprostone, PGE2, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 363-24-6 |
MW: | 352.5 D |
From 35.00€
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Item number: Cay14078-10
bk-MDEA (hydrochloride) (Cay-9001123, ethylone) is a psychotropic cathinone that has been detected in products marketed as bath salts, plant food, and tablets. 3,4-Methylenedioxy-5-methylethcathinone is an analog of bk-MDEA, differing by the addition of a methyl group at the two position of the benzene ring. The...
Keywords: | 3,4-Methylenedioxy-5-methyl-N-ethyl Cathinone, R-MMC, 2-(ethylamino)-1-(7-methyl-1,3-benzodioxol-5-yl)-1-propanone,... |
Application: | Analytical reference standard, Cathinone bk-MDEA analog |
CAS | 2748289-02-1 |
MW: | 271.7 D |
From 266.00€
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Item number: Cay14074-10
The polymyxins are cationic peptides originally isolated from B. polymyxa. They bind and kill Gram-negative bacteria. The B series of polymyxins consist of a cyclic heptapeptide and a tripeptide side chain acylated at the amino terminus by a fatty acid. Polymyxin B1 is a form of polymyxin B which terminates with...
Keywords: | (S)-N-((S)-4-amino-1-(((2S,3R)-1-(((S)-4-amino-1-oxo-1-(((3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-... |
Application: | Antibiotic |
CAS | 4135-11-9 |
MW: | 1203.5 D |
From 161.00€
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Item number: Cay14073-100
Tudor domains are small protein structural motifs of ~50 amino acids related to the "royal family" of methyl readers, which also includes chromo, MBT, PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or with other domains. They are found in many proteins that are involved in RNA...
Keywords: | 53BP1, 53BP1, p53BP1, p53BP1, p53-binding protein 1, p53-binding protein 1, TP53-binding protein 1, TP53-binding protein 1 |
Application: | Methyl reader |
Expressed in: | E.coli |
MW: | 42,6 kD |
465.00€
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Item number: Cay10004970-10
Cloprostenol is a synthetic derivative of prostaglandin F2alpha that is used in veterinary medicine as a luteolytic agent for the induction of estrus and in the treatment of reproductive disorders in cattle, swine, and horses. (+)-5-trans Cloprostenol is a minor impurity produced in the synthesis of...
Keywords: | (+)-5,6-trans Cloprostenol, (+)-5-trans-16-m-chlorophenoxy tetranor PGF2alpha, (+)-5-trans-16-m-chlorophenoxy tetranor... |
Application: | Bioactive lipid assays |
CAS | 57968-81-7 |
MW: | 424.9 D |
From 114.00€
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Item number: Cay15407-100
Budesonide is a glucocorticoid and an agonist of glucocorticoid receptors (EC50 = 45.7 pM in a transactivation assay). It is selective for glucocorticoid over mineralocorticoid receptors (EC50 = 7,620 pM). Budesonide inhibits LPS-induced TNF-alpha release from human peripheral blood mononuclear cells (PBMCs, IC50 =...
Keywords: | 16alpha,17-[butylidenebis(oxy)]-11beta,21-dihydroxy-pregna-1,4-diene-3,20-dione |
Application: | Glucocorticoid receptor agonist |
CAS | 51333-22-3 |
MW: | 430.5 D |
From 60.00€
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Item number: Cay14807-100
3-oxo Stearic acid is an intermediate in the dissociated (or type II) fatty acid biosynthesis that occurs in bacteria and plants. This beta-keto fatty acid is generated following the reaction of hexadecenoyl-acyl-carrier-protein (ACP) with malonyl-ACP by the enzyme beta-ketoacyl-ACP synthase II, which produces 3-oxo...
Keywords: | 3-oxo Octadecanoic Acid, beta-keto Stearic Acid, 3-oxo-octadecanoic acid |
Application: | Fatty acid biosynthesis intermediate |
CAS | 16694-29-4 |
MW: | 298.5 D |
From 77.00€
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Item number: Cay16407-100
Ketoprofen (Cay-10006661) is a non-selective, non-steroidal, anti-inflammatory drug exhibiting IC50 values of 0.5 and 2.33 µM for human recombinant COX-1 and COX-2 (Cay-60122), respectively. Ketoprofen is commonly used in vivo as a racemic mixture of (R)- and (S)-enantiomers. (S)-Ketoprofen is a potent inhibitor of...
Keywords: | (S)-2-(3-benzoylphenyl)Propionic Acid, Dexketoprofen, (S)-3-benzoyl-alpha-methyl-benzeneacetic acid |
Application: | COX1/2 inhibitor |
CAS | 22161-81-5 |
MW: | 254.3 D |
From 43.00€
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Item number: Cay14075-500
Polymyxin B1 isoleucine differs from polymyxin B1 by having isoleucine rather than leucine as a component of the cyclic peptide. Polymyxin B1 isoleucine is comparable to other B polymyxins in its ability to kill P. aeruginosa, A. baumannii, and K. pneumoniae isolates. Its relative pharmacokinetics and nephrotoxicity...
Keywords: | N-((S)-4-amino-1-(((2S,3R)-1-(((S)-4-amino-1-oxo-1-(((3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-12-((S... |
Application: | Antibiotic |
MW: | 1301.6 D |
161.00€
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Item number: Cay40170-10
Semaglutide is an agonist of glucagon-like peptide 1 receptor (GLP-1R, EC50 = 6.2 pM in a reporter assay using BHK cells expressing the human receptor). It decreases blood glucose levels in the db/db mouse model of type 2 diabetes (ED50 = 98%. Formulation: (Request formulation change), A solid. Solubility:...
Keywords: | L-histidyl-2-methylalanyl-L-alpha-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-s... |
Application: | GLP-1R agonist |
CAS | 2924330-56-1 |
MW: | 4113.6 D |
From 117.00€
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Item number: Cay14270-100
Rivastigmine is a cholinesterase (ChE) inhibitor that inhibits butyryl ChE (BChE) and acetyl ChE (AChE, IC50s = 0.037 and 4.15 µM, respectively). It increases levels of secreted amyloid precursor protein (sAPP) and decreases levels of soluble amyloid-beta (1-40) and various N-terminal cleavage products in primary...
Keywords: | Exelon, SDZ-ENA 713, 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester N-ethyl-N-methyl-carbamic acid, 2R,3R-dihydroxybutanedioate |
Application: | AChE / BuChE inhibitor |
CAS | 129101-54-8 |
MW: | 400.4 D |
From 158.00€
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Item number: Cay17010-500
Prostaglandin G2 (PGG2) is the first intermediate in the COX pathway which is stable enough to be isolated and characterized. It is the C-15 hydroperoxide of PGH2. Under normal conditions, PGG2 is quickly metabolized by the peroxidase activity intrinsic to both COX-1 and -2 to give PGH2, which serves as the key...
Keywords: | PGG2, 9alpha,11alpha-epidioxy-15S-hydroperoxy-prosta-5Z,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 51982-36-6 |
MW: | 368.5 D |
From 119.00€
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