- Search results for Cay17471
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12 products were found matching "Cay17471"!
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Item number: Cay17471-25
Lysine-specific demethylase 1 (LSD1) is a protein lysine demethylase that specifically demethylates histone H3 lysine 4 (H3K4) and H3K9, resulting in transcriptional repression. Host LSD1 is also recruited by certain viruses to limit H3K9 methylation, which can repress viral genes necessary for infection....
Keywords: | 4'-[(1R,2S)-2-aminocyclopropyl]-[1,1'-biphenyl]-3-ol |
Application: | LSD1 inhibitor |
CAS | 1357302-64-7 |
MW: | 225.3 D |
From 48.00€
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Item number: Cay17447-1
Mephedrone (Cay-10801) is a designer drug of the phenethylamine class that shares substantial structural similarities with methcathinone (Cay-11709) and methamphetamine (Cay-13997). Compounds with these structural characteristics have psychoactive effects and have been identified in products sold as bath salts and...
Keywords: | 3-methoxy Methedrone, 3,4-DMMA, 1-(3,4-dimethoxyphenyl)-2-(methylamino)-1-propanone, monohydrochloride |
Application: | Analytical reference standard, Mephedrone analog |
CAS | 22930-82-1 |
MW: | 259.7 D |
From 280.00€
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Item number: Cay11747-1
Tipifarnib is a nonpeptidomimetic, CAAX-competitive inhibitor of farnesyltransferase (IC50 = 0.86 nM). It prevents farnesylation of Ras GTPases and has shown potent efficacy in various in vitro and in vivo tumor models.Formal Name:...
Keywords: | R 115777, 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone |
Application: | CAAX-competitive farnesyltransferase inhibitor, Ras GTPase farnesylation inhibitor |
CAS | 192185-72-1 |
MW: | 489.4 D |
From 60.00€
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Item number: Cay17477-1
Cdk5 is a serine/threonine kinase that is predominantly active in neuronal tissues. With p25 or p35, Cdk5 phosphorylates a range of proteins, including histone H1 and tau. Cdk5 substrate is a synthetic peptide (PKTPKKAKKL) corresponding to a sequence of histone H1. It is phosphorylated by Cdk5 with a Km value of 5...
Keywords: | Cyclin-dependent kinase 5 Substrate, L-prolyl-L-lysyl-L-threonyl-L-prolyl-L-lysyl-L-lysyl-L-alanyl-L-lysyl-L-lysyl-L-leucine |
Application: | Cdk5 substrate |
MW: | 1138.5 D |
From 77.00€
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Item number: Cay17478-1
The C2 domain of conventional PKC isoforms mediates calcium-dependent translocation. Peptides from that region can block PKC translocation and inhibit function, both in cells and cell lysates. PKCalpha (C2-4) inhibitor peptide is a synthetic peptide that blocks PKC activity in HepG2 cells stimulated with calcium and...
Keywords: | Protein Kinase Calpha (C2-4) Inhibitor Peptide |
Application: | PKC alpha inhibitor |
MW: | 1107.2 D |
From 129.00€
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Item number: Cay17474-1
Son of sevenless homolog 1 (Sos1) is a guanine nucleotide exchange factor (GEF) that directs the exchange of Ras-GDP to Ras-GTP by binding to SH3 domains of the growth factor receptor-bound protein 2 (Grb2), leading to the activation of ERK. Ras inhibitory peptide is a synthetic peptide that contains the sequence...
Keywords: | Sos SH3 Domain Inhibitor |
Application: | SOS1-Grb3 interaction inhibitor |
CAS | 159088-48-9 |
MW: | 1170.4 D |
From 92.00€
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Item number: Cay17473-1
The protein p53, often called the 'guardian of the genome,' is a transcription factor that is activated in response to cellular stress (low oxygen levels, heat shock, DNA damage, etc.) and acts to prevent further proliferation of the stressed cell by promoting cell cycle arrest or apoptosis. Its role as a tumor...
Keywords: | SAR405838,... |
Application: | MDM2-p53 interaction inhibitor |
CAS | 1303607-60-4 |
MW: | 562.5 D |
From 60.00€
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Item number: Cay17470-1
MitoB-d15 is intended for use as an internal standard for the quantification of MitoB (Cay-17116) by GC- or LC-MS. MitoB is a ratiometric mass spectrometry probe that can be used for assessing changes in H2O2 within mitochondria in vivo. MitoB contains a triphenylphosphonium cation component that drives its...
Keywords: | [(3-boronophenyl)methyl]triphenyl-d15-phosphonium, monobromide |
Application: | Internal standard, GC-MS, LC-MS |
MW: | 492.2 D |
From 92.00€
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Item number: Cay17476-1
Protein kinase C? (PKC?) is a calcium-independent, phospholipid- and diacylglycerol-dependent serine/threonine kinase involved in diverse signaling pathways, including those involved in neuronal signaling, cytoskeletal function, and inflammation. PKC? inhibitor peptide is a synthetic peptide corresponding to an...
Keywords: | eV1-2, Protein Kinase Ce Inhibitor Peptide |
Application: | PKC epsilon translocation inhibitor |
CAS | 182683-50-7 |
MW: | 844 D |
From 43.00€
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Item number: Cay17472-1
ML-324 is a cell-permeable inhibitor of JMJD2E (KDM4DL, IC50 = 920 nM) that is inactive against lysine-specific demethylase, LSD1. It reduces the expression of immediate early genes of Herpes simplex virus (IC50 = ~10 µM) and human cytomegalovirus, blocks viral infection, and suppresses the level of viral...
Keywords: | CID-44143209, N-[3-(dimethylamino)propyl]-4-(8-hydroxy-6-quinolinyl)-benzamide |
Application: | JMJD2E inhibitor |
CAS | 1222800-79-4 |
MW: | 349.4 D |
From 43.00€
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Item number: Cay17475-1
NF-kappaB inhibitor (Cay-17493) is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-kappaB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. It blocks the nuclear import of p105 in cells treated with activators of NF-kappaB...
Keywords: | SN50M |
Application: | NF-kappaB inhibitor (Cay17493) control |
CAS | 201608-17-5 |
MW: | 2668.3 D |
From 125.00€
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Item number: Cay17479-1
Bombesin is a peptide, originally isolated from the skin of the European fire-bellied toad, with pressor and sympathoexcitatory activity. Its three receptors are distributed throughout the central and peripheral nervous system and are involved in gastric acid secretion, emotional response, temperature control,...
Keywords: | N-(2-methyl-1-oxopropyl)-7-D-alanine-9-(N-methyl-L-leucinamide)-3-9-neuromedin C |
Application: | GRP/bombesin receptor 2 antagonist |
CAS | 124001-41-8 |
MW: | 916.1 D |
From 205.00€
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