12 products were found matching "Cay17471"!

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OG-L002
OG-L002

Item number: Cay17471-25

Lysine-specific demethylase 1 (LSD1) is a protein lysine demethylase that specifically demethylates histone H3 lysine 4 (H3K4) and H3K9, resulting in transcriptional repression. Host LSD1 is also recruited by certain viruses to limit H3K9 methylation, which can repress viral genes necessary for infection....
Keywords: 4'-[(1R,2S)-2-aminocyclopropyl]-[1,1'-biphenyl]-3-ol
Application: LSD1 inhibitor
CAS 1357302-64-7
MW: 225.3 D
From 48.00€ *
Review
3,4-Dimethoxymethcathinone (hydrochloride)
3,4-Dimethoxymethcathinone (hydrochloride)

Item number: Cay17447-1

Mephedrone (Cay-10801) is a designer drug of the phenethylamine class that shares substantial structural similarities with methcathinone (Cay-11709) and methamphetamine (Cay-13997). Compounds with these structural characteristics have psychoactive effects and have been identified in products sold as bath salts and...
Keywords: 3-methoxy Methedrone, 3,4-DMMA, 1-(3,4-dimethoxyphenyl)-2-(methylamino)-1-propanone, monohydrochloride
Application: Analytical reference standard, Mephedrone analog
CAS 22930-82-1
MW: 259.7 D
From 280.00€ *
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Tipifarnib
Tipifarnib

Item number: Cay11747-1

Tipifarnib is a nonpeptidomimetic, CAAX-competitive inhibitor of farnesyltransferase (IC50 = 0.86 nM). It prevents farnesylation of Ras GTPases and has shown potent efficacy in various in vitro and in vivo tumor models.Formal Name:...
Keywords: R 115777, 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone
Application: CAAX-competitive farnesyltransferase inhibitor, Ras GTPase farnesylation inhibitor
CAS 192185-72-1
MW: 489.4 D
From 60.00€ *
Review
Cdk5 Substrate
Cdk5 Substrate

Item number: Cay17477-1

Cdk5 is a serine/threonine kinase that is predominantly active in neuronal tissues. With p25 or p35, Cdk5 phosphorylates a range of proteins, including histone H1 and tau. Cdk5 substrate is a synthetic peptide (PKTPKKAKKL) corresponding to a sequence of histone H1. It is phosphorylated by Cdk5 with a Km value of 5...
Keywords: Cyclin-dependent kinase 5 Substrate, L-prolyl-L-lysyl-L-threonyl-L-prolyl-L-lysyl-L-lysyl-L-alanyl-L-lysyl-L-lysyl-L-leucine
Application: Cdk5 substrate
MW: 1138.5 D
From 77.00€ *
Review
PKCalpha (C2-4) Inhibitor Peptide
PKCalpha (C2-4) Inhibitor Peptide

Item number: Cay17478-1

The C2 domain of conventional PKC isoforms mediates calcium-dependent translocation. Peptides from that region can block PKC translocation and inhibit function, both in cells and cell lysates. PKCalpha (C2-4) inhibitor peptide is a synthetic peptide that blocks PKC activity in HepG2 cells stimulated with calcium and...
Keywords: Protein Kinase Calpha (C2-4) Inhibitor Peptide
Application: PKC alpha inhibitor
MW: 1107.2 D
From 129.00€ *
Review
Ras Inhibitory Peptide
Ras Inhibitory Peptide

Item number: Cay17474-1

Son of sevenless homolog 1 (Sos1) is a guanine nucleotide exchange factor (GEF) that directs the exchange of Ras-GDP to Ras-GTP by binding to SH3 domains of the growth factor receptor-bound protein 2 (Grb2), leading to the activation of ERK. Ras inhibitory peptide is a synthetic peptide that contains the sequence...
Keywords: Sos SH3 Domain Inhibitor
Application: SOS1-Grb3 interaction inhibitor
CAS 159088-48-9
MW: 1170.4 D
From 92.00€ *
Review
MI-77301
MI-77301

Item number: Cay17473-1

The protein p53, often called the 'guardian of the genome,' is a transcription factor that is activated in response to cellular stress (low oxygen levels, heat shock, DNA damage, etc.) and acts to prevent further proliferation of the stressed cell by promoting cell cycle arrest or apoptosis. Its role as a tumor...
Keywords: SAR405838,...
Application: MDM2-p53 interaction inhibitor
CAS 1303607-60-4
MW: 562.5 D
From 60.00€ *
Review
MitoB-d15
MitoB-d15

Item number: Cay17470-1

MitoB-d15 is intended for use as an internal standard for the quantification of MitoB (Cay-17116) by GC- or LC-MS. MitoB is a ratiometric mass spectrometry probe that can be used for assessing changes in H2O2 within mitochondria in vivo. MitoB contains a triphenylphosphonium cation component that drives its...
Keywords: [(3-boronophenyl)methyl]triphenyl-d15-phosphonium, monobromide
Application: Internal standard, GC-MS, LC-MS
MW: 492.2 D
From 92.00€ *
Review
PKCepsilon Inhibitor Peptide
PKCepsilon Inhibitor Peptide

Item number: Cay17476-1

Protein kinase C? (PKC?) is a calcium-independent, phospholipid- and diacylglycerol-dependent serine/threonine kinase involved in diverse signaling pathways, including those involved in neuronal signaling, cytoskeletal function, and inflammation. PKC? inhibitor peptide is a synthetic peptide corresponding to an...
Keywords: eV1-2, Protein Kinase Ce Inhibitor Peptide
Application: PKC epsilon translocation inhibitor
CAS 182683-50-7
MW: 844 D
From 43.00€ *
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ML-324
ML-324

Item number: Cay17472-1

ML-324 is a cell-permeable inhibitor of JMJD2E (KDM4DL, IC50 = 920 nM) that is inactive against lysine-specific demethylase, LSD1. It reduces the expression of immediate early genes of Herpes simplex virus (IC50 = ~10 µM) and human cytomegalovirus, blocks viral infection, and suppresses the level of viral...
Keywords: CID-44143209, N-[3-(dimethylamino)propyl]-4-(8-hydroxy-6-quinolinyl)-benzamide
Application: JMJD2E inhibitor
CAS 1222800-79-4
MW: 349.4 D
From 43.00€ *
Review
NF-kappaB Control
NF-kappaB Control

Item number: Cay17475-1

NF-kappaB inhibitor (Cay-17493) is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-kappaB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. It blocks the nuclear import of p105 in cells treated with activators of NF-kappaB...
Keywords: SN50M
Application: NF-kappaB inhibitor (Cay17493) control
CAS 201608-17-5
MW: 2668.3 D
From 125.00€ *
Review
ICI 216140
ICI 216140

Item number: Cay17479-1

Bombesin is a peptide, originally isolated from the skin of the European fire-bellied toad, with pressor and sympathoexcitatory activity. Its three receptors are distributed throughout the central and peripheral nervous system and are involved in gastric acid secretion, emotional response, temperature control,...
Keywords: N-(2-methyl-1-oxopropyl)-7-D-alanine-9-(N-methyl-L-leucinamide)-3-9-neuromedin C
Application: GRP/bombesin receptor 2 antagonist
CAS 124001-41-8
MW: 916.1 D
From 205.00€ *
Review