OCH

OCH
%
Item number Size Datasheet Manual SDS Delivery time Quantity Discount Price
AG-CR1-3593-C250 250 µg -

3 - 9 business days*

10 %
154.00€
138.60€
AG-CR1-3593-M001 1 mg -

3 - 9 business days*

10 %
308.00€
277.20€
 
White to off-white solid. Soluble in DMSO, 100% ethanol (warm) or methanol (warm). Truncated... more
Product information "OCH"
White to off-white solid. Soluble in DMSO, 100% ethanol (warm) or methanol (warm). Truncated analog of alpha-GalCer, iNKT cell glycolipid agonist, Immunosuppressive, Th2 polarizing. Stimulation of NKT with OCH results in release of primarily Th2 cytokine compared to stimulation with alpha-GalCer, which results in release of a mixture of Th1 and Th2 cytokines, Induces stronger interleukin-4 (IL-4) secretion and weaker interferon-gamma (IFN-gamma) secretion than alpha-GalCer both in vitro and in vivo, Inducer of interleukin-10 (IL-10) and suppressor of diabetes, Shown to prevent experimental autoimmune encephalomyelitis (EAE) in mice, an animal model of multiple sclerosis, Has beneficial effects on type I diabetes in NOD mice, Suppressor of collagen-induced arthritis, Might be useful for immunotherapy of transplant rejection.
Keywords: (2S,3S,4R)-1-O-(alpha-D-Galactopyranosyl)-N-tetracosanoyl-2-amino-1,3,4-nonanetriol)
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-CR1-3593

Properties

Application: alpha-galactosylceramide analog
MW: 704 D
Formula: C39H77NO9
Purity: >95%
Format: Solid

Database Information

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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