(±)-Nutlin-3

(±)-Nutlin-3
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10004372-1 1 mg -

6 - 10 business days*

50.00€
Cay10004372-5 5 mg -

6 - 10 business days*

146.00€
Cay10004372-10 10 mg -

6 - 10 business days*

267.00€
Cay10004372-50 50 mg -

6 - 10 business days*

658.00€
 
(±)-Nutlin-3 is a racemic mixture of the p53-Mdm2 protein-protein interaction inhibitor... more
Product information "(±)-Nutlin-3"

(±)-Nutlin-3 is a racemic mixture of the p53-Mdm2 protein-protein interaction inhibitor (-)-nutlin-3 (Cay-18585) and its less active enantiomer (+)-nutlin-3 (Cay-10009816). In vivo, (±)-nutlin-3 (200 mg/kg twice daily) reduces tumor volume in an SJSA-1 osteosarcoma mouse xenograft model.Formal Name: rel-4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-piperazinone. CAS Number: 548472-68-0. Molecular Formula: C30H30Cl2N4O4. Formula Weight: 581.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 25 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS (pH 7.2) 1:10: .1 mg/ml. SMILES: C(=O)(N1[C@H]([C@H](N=C1C2=C(OC(C)C)C=C(OC)C=C2)C3=CC=C(Cl)C=C3)C4=CC=C(Cl)C=C4)N5CC(=O)NCC5. InChi Code: InChI=1S/C30H30Cl2N4O4/c1-18(2)40-25-16-23(39-3)12-13-24(25)29-34-27(19-4-8-21(31)9-5-19)28(20-6-10-22(32)11-7-20)36(29)30(38)35-15-14-33-26(37)17-35/h4-13,16,18,27-28H,14-15,17H2,1-3H3,(H,33,37)/t27-,28+/m0/s1. InChi Key: BDUHCSBCVGXTJM-WUFINQPMSA-N.

Keywords: rel-4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-piperazinone
Supplier: Cayman Chemical
Supplier-Nr: 10004372

Properties

Application: Cell cycle arrest promotor
MW: 581.5 D
Formula: C30H30Cl2N4O4
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 548472-68-0| Matching products
KEGG ID : K06643 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315, H319, H335
P Phrases: P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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