Notch reporter cell line, 1.5x10(6) cells

Notch reporter cell line, 1.5x10(6) cells

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
BPS-60652	2 vials (2 vials)		-	-	3 - 15 business days*		3,104.00€

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The Notch CSL Reporter - HEK293 cell line contains the firefly luciferase gene under the control... more

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Product information "Notch reporter cell line, 1.5x10(6) cells"

The Notch CSL Reporter - HEK293 cell line contains the firefly luciferase gene under the control of Notch-response elements (CSL responsive elements) alone with expression construct for Notch1 E (NOTCH1 that has a deletion of the entire extracellular domain) stably integrated into HEK293 cells. Inside the cells, the Notch1 E can be cleaved by gamma-secretase. The active Notch1 NICD is released to nucleus and induces the constitutive expression of luciferase reporter. The cell line is validated for the inhibition of the expression of luciferase reporter using a known inhibitor of the Notch signaling pathway.

Keywords:	Notch, NICD, PKA, cAMP, luciferase reporter,
Supplier:	BPS Bioscience
Supplier-Nr:	60652

Properties

Application:	Notch signaling assays, inhibitor screening
Host:	HEK293
Species reactivity:	human
Format:	Solution

Database Information

KEGG ID :

K02599 | Matching products

Handling & Safety

Storage:	Liquid nitrogen
Shipping:	-80°C (International: -80°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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