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Anti-INI-1/SNF5
Item number: ABE-11-7550-100
SNF5/INI1 is the core subunit of the SWI/SNF chromatin remodeling complex that contributes to the regulation of chromatin structure. It is a tumor suppressor in humans and mice, with an essential role in early embryonic development. SNF5 interacts with UV damage recognition factor XPC and colocalizes at the damage...
| Keywords: | Anti-hSNF5, Anti-BAF47, Anti-SMARCB1, Anti-SNF5 homolog, Anti-BRG1-associated factor 47, Anti-Integrase interactor 1... |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human |
387.00€
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328.95€
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Anti-INI-1/SNF5
Item number: ABE-11-7550-25
SNF5/INI1 is the core subunit of the SWI/SNF chromatin remodeling complex that contributes to the regulation of chromatin structure. It is a tumor suppressor in humans and mice, with an essential role in early embryonic development. SNF5 interacts with UV damage recognition factor XPC and colocalizes at the damage...
| Keywords: | Anti-hSNF5, Anti-BAF47, Anti-SMARCB1, Anti-SNF5 homolog, Anti-BRG1-associated factor 47, Anti-Integrase interactor 1... |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human |
134.00€
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BAY 60-7550
Item number: Cay10011135-1
The second messengers cAMP and cGMP are important mediators of signal transduction and hence a wide range of cellular processes including vasodilation and synaptic plasticity. Type 2 cyclic nucleotide phosphodiesterases (PDE2) isoforms inactivate cAMP and cGMP by hydrolyzing the phosphodiester bond. BAY 60-7550 is a...
| Keywords: | 2-[(3,4-dimethoxyphenyl)methyl]-7-[(1R)-1-hydroxyethyl]-4-phenylbutyl]-5-methyl-imidazo[5,1-f][1,2,4]triazin-4(1H)-one |
| Application: | PDE2 inhibitor |
| CAS | 439083-90-6 |
| MW: | 476.6 D |
From 125.00€
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NEW
AZ 7550 (hydrochloride)
Item number: Cay40753-5
AZ 7550 is an active metabolite of AZ 9291 (Cay-16237). It inhibits the insulin-like growth factor 1 receptor (IGF-1R) in a cell-free assay (IC50 = 1.6 µM). It inhibits EGFR autophosphorylation in H1975 and PC-9 cells expressing the respective constitutively active mutants EGFRT790M/L858R and EGFRExon19del (IC50s =...
| Keywords: | N-[4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[methyl[2-(methylamino)ethyl]amino]phenyl]-2-propenamid... |
| Application: | AZ 9291 active metabolite, mutant-selective EGFR inhibitor |
| MW: | 485.6 D |
From 34.00€
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AZ 7550
Item number: Cay34766-5
AZ 7550 is an active metabolite of AZ 9291 (Cay-16237). It inhibits the insulin-like growth factor 1 receptor (IGF-1R) in a cell-free assay (IC50 = 1.6 µM). It inhibits EGFR autophosphorylation in H1975 and PC-9 cells expressing the respective constitutively active mutants EGFRT790M/L858R and EGFRExon19del (IC50s =...
| Keywords: | N-[4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[methyl[2-(methylamino)ethyl]amino]phenyl]-2-propenamide |
| Application: | AZ 9291 active metabolite, IGF1R inhibitor |
| CAS | 1421373-99-0 |
| MW: | 485.6 D |
From 64.00€
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