- Search results for Cay70650
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10 products were found matching "Cay70650"!
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Item number: Cay70650-10000
Niflumic acid is a selective inhibitor of COX-2. The IC50 values are 16 and 0.1 µM for human recombinant COX-1 and -2, respectively. The Ki values are 2 and 0.02 µM for ovine COX-1 and -2, respectively.Formal Name: 2-[[3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid. CAS Number: 4394-00-7. Synonyms:...
Keywords: | Actol, Donalgin, Nifluril, UP83, 2-[[3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid |
Application: | COX-2 inhibitor |
CAS | 4394-00-7 |
MW: | 282.2 D |
From 43.00€
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Item number: Cay70675-50
trans-Resveratrol is a polyphenol that has been found in grapes and has diverse biological activities. It inhibits the cyclooxygenase and hydroperoxidase activities of COX-1 (EC50s = 15 and 3.7 µM, respectively) but not COX-2 (EC50s = >100 µM and 85 µM, respectively). trans-Resveratrol (200 µM) also activates...
Keywords: | (E)-Resveratrol, 5-[(1E)-2-(4-hydroxyphenyl)ethenyl]-1,3-benzenediol |
Application: | COX-1 inhibitor |
CAS | 501-36-0 |
MW: | 228.2 D |
From 34.00€
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Item number: Cay70610-50
Baicalein is a flavonoid originally isolated from the roots of S. baicalensis that has diverse biological activities. It inhibits human platelet 12-lipoxygenase (12-LO) and human reticulocyte 15-LO-1 (IC50s = 0.64 and 1.6 µM, respectively) but is less potent at 15-LO-1 when the detergent Triton-X is present (IC50 =...
Keywords: | 5,6,7-trihydroxyflavone |
Application: | Lipid peroxidation inhibitor |
CAS | 491-67-8 |
MW: | 270.2 D |
From 24.00€
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Item number: Cay70604-50
3,4-Dihydroxyphenyl ethanol is a phenolic component of olive oil that inhibits both 12- and 5-LO. The IC50 values for the inhibition of rat platelet 12-LO and rat neutrophil 5-LO are 4.2 and 13 µM, respectively. It does not inhibit, and may actually enhance, COX activity. 3,4-Dihydroxyphenyl ethanol also protects...
Keywords: | 3-Hydroxytyrosol, Ba2774, DOPET, 4-(2-hydroxyethyl)-1,2-benzenediol |
Application: | Bioactive lipid assays |
CAS | 10597-60-1 |
MW: | 154.2 D |
From 43.00€
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Item number: Cay70665-50
Arachidonoyl serotonin is an inhibitor of fatty acid amide hydrolase (FAAH), the enzyme responsible for inactivation of anandamide and other endogenous cannabinoids. It inhibits the FAAH activity isolated from mouse neuroblastoma cells with an IC50 value of 12 µM. Both the Km and the Vmax of the enzyme are affected,...
Keywords: | AA-5HT, N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-5Z,8Z,11Z,14Z-eicosatetraenamide |
Application: | FAAH inhibitor |
CAS | 187947-37-1 |
MW: | 462.7 D |
From 66.00€
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Item number: Cay70655-10
SC-58125 is a member of the diaryl heterocycle group of selective COX-2 inhibitors which includes MK 966 (rofecoxib), DUP-697, and celecoxib. SC-58125 is a potent and time-dependent inhibitor of COX-2. When tested on the isolated recombinant enzymes, SC-58125 is at least 150 times more potent in the inhibition of...
Keywords: | 5-(4-fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazole |
Application: | COX2 inhibitor |
CAS | 162054-19-5 |
MW: | 384.3 D |
From 23.00€
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Item number: Cay70645-50
DuP-697 is a member of the diaryl heterocycle group of selective COX-2 inhibitors which includes MK-966 (rofecoxib), SC-58125, and celecoxib. DuP-697 is a potent and time-dependent inhibitor of COX-2. When tested on isolated recombinant enzymes, DuP-697 is at least 50 times more potent in the inhibition of COX-2...
Keywords: | 5-bromo-2-(4-fluorophenyl)-3-(4-(methylsulfonyl)phenyl)-thiophene |
Application: | COX-2 inhibitor |
CAS | 88149-94-4 |
MW: | 411.3 D |
From 147.00€
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Item number: Cay70600-50
REV 5901 is an antagonist of cysteinyl-leukotriene receptors with a Ki value of 0.7 µM for guinea pig lung membranes. It is also an inhibitor of rat neutrophil 5-LO with an IC50 value of 0.12 µM.Formal Name: alpha-pentyl-3-(2-quinolinylmethoxy)-benzenemethanol. CAS Number: 101910-24-1. Molecular Formula: C22H25NO2....
Keywords: | alpha-pentyl-3-(2-quinolinylmethoxy)-benzenemethanol |
Application: | 5-LO inhibitor |
CAS | 101910-24-1 |
MW: | 335.4 D |
From 43.00€
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Item number: Cay70620-50
6-MNA is a competitive, non-selective COX inhibitor. The Ki values for ovine COX-1 and -2 are 21 and 19 µM, respectively. The IC50 values are 70 and 20 µM for human recombinant COX-1 and -2, respectively.Formal Name: 6-methoxy-2-naphthaleneacetic acid. CAS Number: 23981-47-7. Synonyms: 6-MNA. Molecular Formula:...
Keywords: | 6-MNA, 6-methoxy-2-naphthaleneacetic acid |
Application: | COX inhibitor |
CAS | 23981-47-7 |
MW: | 216.2 D |
From 43.00€
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Item number: Cay70670-50
Valeroyl salicylate is a selective, irreversible inhibitor of cyclooxygenase-1 (COX-1). The IC50 values for ovine COX-1 and -2 are 0.8 and 15 mM, respectively. The half-lives for inactivation of human recombinant and ovine COX-1 in the presence of 500 µM valeroyl salicylate are 12 and 45 minutes, respectively.Formal...
Keywords: | 2-Valeryloxybenzoic Acid, 2-[(1-oxopentyl)oxy]-benzoic acid |
Application: | COX-1 inhibitor |
CAS | 64206-54-8 |
MW: | 222.2 D |
From 43.00€
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