Neuregulin-1 beta2 / Heregulin-b2, human recombinant (rHuNRG1)

Neuregulin-1 beta2 / Heregulin-b2, human recombinant (rHuNRG1)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
94966.10 10 µg - -

3 - 10 business days*

94.00€
94966.50 50 µg - -

3 - 10 business days*

208.00€
94966.1 1 mg - -

3 - 10 business days*

1,966.00€
 
Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and... more
Product information "Neuregulin-1 beta2 / Heregulin-b2, human recombinant (rHuNRG1)"
Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells. inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction. stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells. stimulating Schwann cell proliferation. implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 61 amino acids
Keywords: Neuregulin-1, NRG1, GGF, HGL, HRGA, NDF, SMDF, HRG, ARIA, GGF2, HRG1
Supplier: Biomol GmbH
Supplier-Nr: 94966

Properties

Application: Cell culture
Conjugate: No
Host: E.coli
Species reactivity: human
MW: 7055 D
Purity: >96%
Format: Lyophilized

Database Information

KEGG ID : K05455 | Matching products
UniProt ID : Q02297 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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