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Ononin
Ononin

Item number: Cay27046-10

Ononin is a glycoside isoflavone that has been found in soybeans and A. mongholicus and has anti-inflammatory and neuroprotective activities. Ononin (5 µM) inhibits LPS-induced production of nitrite, prostaglandin E2 (PGE2, Cay-14010), and the pro-inflammatory cytokines IL-1beta, IL-6, and TNF-alpha by RAW 264.7...
Keywords: Formononetin 7-O-Glucoside, Formononetin 7-O-beta-D-Glucopyranoside, Formononetin Glucoside,...
Application: Antiinflammatory, neuroprotective glycoside isoflavone
CAS 486-62-4
MW: 430.4 D
From 163.00€ *
Review
BIIB021
BIIB021

Item number: BPS-27046

BIIB021 is an orally available, synthetic small-molecule Hsp90 inhibitor. It binds in the ATP-binding pocket of Hsp90 (Ki = 1.7 ± 0.4 nM) and induces HER-2 degradation with an EC50 of 38 ± 10 nM in MCF-7 cells. It ncreases expression of the heat shock proteins Hsp90alpha and Hsp70, but has no effect on expression of...
Keywords: CNF2024,
Application: Hsp90 inhibitor
MW: 318.8 D
276.00€ *
Review