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Naringenin
Naringenin

Item number: Cay14173-1

Naringenin is a citrus-derived flavonoid that inhibits CYP3A4 activity in human liver microsomes (IC50s = 139-188 µM). At 100 mg/kg/day, naringenin selectively inhibits the transcription of Smad3 and directly down-regulates TGF-beta1, significantly reducing lung metastasis in mice with bleomycin-induced pulmonary...
Keywords: NSC 11855, NSC 34875, S-Dihydrogenistein, Salipurol, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Application: CYP3A4 inhibitor
CAS 67604-48-2
MW: 272.3 D
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