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ZM 522
ZM 522

Item number: Cay37904-50

ZM 522 is an inhibitor of ecto-5'-nucleotidase, also known as CD73 (IC50s = 0.56 and 3.06 µM for the human and mouse enzymes, respectively), and a derivative of the triterpenoid betulinic acid (Cay-11686). It increases the levels of IFN-gamma secreted by isolated mouse spleen cells when used at a concentration of 10...
Keywords: 3beta-[(4-fluorobenzoyl)oxy]-lup-20(29)-en-28-oic acid
Application: Ecto-5'-nucleotidase inhibitor
CAS 1454575-38-2
MW: 578.8 D
From 48.00€ *
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SNS-032
SNS-032

Item number: Cay17904-50

Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. SNS-032 is an ATP-competitive inhibitor of Cdk9, 2, and 7 with IC50 values of 4, 38, and 62 nM, respectively. It is selective for these kinases and displays no additional activity...
Keywords: BMS-387032, N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide
Application: Cdk9 / Cdk2 / Cdk7 inhibitor
CAS 345627-80-7
MW: 380.5 D
From 60.00€ *
Review