Nampt, Recombinant, Human (His) (Visfatin/PBEF, PBEF1, Pre-B Cell Colony Enhancing Factor 1, Nicotin

Nampt, Recombinant, Human (His) (Visfatin/PBEF, PBEF1, Pre-B Cell Colony Enhancing Factor 1, Nicotin
Item number Size Datasheet Manual SDS Delivery time Quantity Price
045067.50 50 µg - -

3 - 19 business days*

606.00€
 
Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF,... more
Product information "Nampt, Recombinant, Human (His) (Visfatin/PBEF, PBEF1, Pre-B Cell Colony Enhancing Factor 1, Nicotin"
Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an 52kD adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity. Recombinant protein corresponding to aa1-491from Intracellular human Nampt fused at the C-terminus to a His-tag. , Biological Activity:, Shows adipogenic effects in stimulated differentiating 3T3-L1 cells. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.e made in assay buffer..
Keywords: PBEF, NAMPT, Nampt, Visfatin, NAmPRTase, EC=2.4.2.12, Pre-B cell-enhancing factor, Pre-B-cell colony-enhancing factor 1, Nicotinamide phosphoribosyltransferase
Supplier: United States Biological
Supplier-Nr: 045067

Properties

Conjugate: No
Species reactivity: human
Format: Highly Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Nampt, Recombinant, Human (His) (Visfatin/PBEF, PBEF1, Pre-B Cell Colony Enhancing Factor 1, Nicotin"
Write a review
or to review a product.
Viewed