- Search results for Cay15520
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5 products were found matching "Cay15520"!
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Item number: Cay15520-100
Naltrexone (Cay-15520) is an analytical reference material categorized as an opioid antagonist. Formulations containing naltrexone have been used in the treatment of alcohol dependence and in the prevention of relapse to opioid dependence. This product is intended for research and forensic applications.Formal Name:...
Keywords: | NIH 8503, 17-(cyclopropylmethyl)-4,5alpha-epoxy-3,14-dihydroxy-morphinan-6-one, monohydrochloride |
Application: | Analytical reference material, Opioid antagonist |
CAS | 16676-29-2 |
MW: | 377.9 D |
From 109.00€
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Item number: Cay15220-10
Dovitinib is a multi-kinase inhibitor. It inhibits the receptor tyrosine kinases FLT3, CSF1R, and c-Kit (IC50s = 1, 36, and 2 nM, respectively), as well as FGFR1, FGFR3, VEGFR1-3, PDFGRalpha, and PDGFRbeta (IC50s = 8, 9, 10, 13, 8, 27, and 210 nM, respectively). Dovitinib inhibits proliferation of human multiple...
Keywords: | CHIR-258, TKI-258, 4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone |
Application: | PDGFRB / VEGFR2 / FGFR1 inhibitor |
CAS | 405169-16-6 |
MW: | 392.4 D |
From 163.00€
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Item number: Cay15200-10
HDAC6 is a predominantly cytoplasmic enzyme that targets alpha-tubulin, cortactin, and heat shock protein 90, as well as other substrates. In this way, it impacts development, proliferation, invasion, and tumorigenesis. HDAC6 Inhibitor is a potent and selective inhibitor of HDAC6 (IC50 = 36 nM) that poorly blocks...
Keywords: | Histone Deacetylase 6, 1,2,3,4-tetrahydro-N-hydroxy-2-[(1-methyl-1H-pyrrol-2-yl)carbonyl]-6-isoquinolinecarboxamide |
Application: | Cell-permeable HDAC6 inhibitor |
CAS | 1259296-46-2 |
MW: | 299.3 D |
From 77.00€
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Item number: Cay11520-500
Thioredoxin 1 (Trx1) is a thiol-disulfide oxidoreductase and part of the antioxidant thioredoxin system that is involved in the maintenance of cellular thiol redox homeostasis. It is ubiquitously expressed, localizes primarily to the cytoplasm with some nuclear localization, and is upregulated in and released from...
Keywords: | TXN, Trx, ADF, Trx, ADF, TRDX, SASP, SASP, Thioredoxin, Thioredoxin, ATL-derived factor, ATL-derived factor, Hom s Trx... |
Application: | Enzyme assays |
530.00€
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Item number: Cay15526-10
ALK5 inhibitor II is a cell permeable, selective inhibitor of the TGF-beta type 1 activin like kinase receptor ALK5 (IC50s = 4, 18, and 23 nM for ALK5 autophosphorylation, TGF-beta cellular assay, and ALK5 binding in HepG2 cells, respectively). This inhibitor demonstrated less potent activity (IC50s > 16 µM) when...
Keywords: | E 616452, RepSox, SJN 2511, 2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine, monohydrochloride |
Application: | TGFBR1 inhibitor |
CAS | 2319939-07-4 |
MW: | 323.8 D |
From 44.00€
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