- Search results for Cay10757-25
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9 products were found matching "Cay10757-25"!
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Item number: Cay17572-5
Guanidinoethyl sulfonate, also known as taurocyamine, is a natural guanidine-taurine analog derived from taurine. It is an intermediate of taurine and hypotaurine metabolism and is phosphorylated by taurocyamine kinase. Guanidinoethyl sulfonate competitively inhibits taurine uptake by sodium-dependent taurine...
Keywords: | NSC 667063, Taurocyamine, 2-[(aminoiminomethyl)amino]-ethanesulfonic acid |
Application: | Taurine & hypotaurine metabolism intermediate |
CAS | 543-18-0 |
MW: | 167.2 D |
From 68.00€
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Item number: Cay10572-5
Scriptaid is a histone deacetylase inhibitor that has an optimal concentration of 6-8 µM in a cell-based assay, is less toxic than trichostatin A, and works in a wide variety of biological systems. It induces cell cycle arrest in colon cancer cells in culture and inhibits tumor growth in vitro and in vivo. Scriptaid...
Keywords: | GCK 1026, N-hydroxy-1,3-dioxo-1H-benz[de]isoquinoline-2(3H)-hexananmide |
Application: | Histone deacetylase inhibitor |
CAS | 287383-59-9 |
MW: | 326.4 D |
From 48.00€
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Item number: Cay10727-5
PtdIns-(3,4,5)-P3 (PIP3) serves as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains such as phosphatidylinositol 3-kinase (PI3K) or PTEN. Protein binding to PIP3 is important for cytoskeletal rearrangement and membrane trafficking and initiates an intricate signaling...
Keywords: | N-[[(2-hydroxy-5-nitrophenyl)amino]thioxomethyl]-3,5-dimethyl-benzamide |
Application: | PIP3/Akt PH domain binding inhibitor |
CAS | 701947-53-7 |
MW: | 345.4 D |
From 35.00€
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Item number: Cay15725-25
Bufalin is a cardiotonic steroid first isolated from toad venom and used in traditional Asian medicine. It inhibits the Na+/K+-ATPase transporter (Kds = 42, 45, and 40 nM for the alpha1, alpha2, and alpha3 subunits, respectively). Intravenously administered bufalin is cleared rapidly, with a plasma half-life of 25...
Keywords: | NSC 89595, (3beta,5beta)-3,14-dihydroxy-bufa-20,22-dienolide |
Application: | Na+/K+-ATPase transporter inhibitor, SRC-1/3 inhibitor |
CAS | 465-21-4 |
MW: | 386.5 D |
From 77.00€
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Item number: Cay10755-50
Post-translational modification of histones by methylation of lysine residues can promote transcriptional activation or repression. G9a-like protein (GLP) and G9a are SET domain-containing methyltransferases that specifically mono- and di-methylate histone H3 at lysine 9 (H3K9). Methylation of H3K9 by a GLP/G9a...
Keywords: | GLP, GLP, GLP1, GLP1, EHMT1, EUHMTASE1, Eu-HMTase1, Eu-HMTase1, H3-K9-HMTase 5, H3-K9-HMTase 5, G9a-like protein 1,... |
Application: | Enzyme activity |
Expressed in: | E.coli |
MW: | 60,3 kD |
530.00€
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COVID-19 Research
Item number: Cay16757-250
Ribavirin is an antiviral guanosine nucleoside analog. Upon entry into cells, ribavirin is metabolized to an active triphosphate form that induces viral RNA chain termination and inhibits viral polymerases. It reduces replication in a panel of seven RNA and four DNA viruses in Vero cells (EC50s = 2-95 µg/ml)....
Keywords: | NSC 163039, 1-beta-D-ribofuranosyl-1H-1,2,4-triazole-3-carboxamide |
Application: | Antiviral guanosine analog |
CAS | 36791-04-5 |
MW: | 244.2 D |
From 43.00€
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Item number: Cay28464-1
CAY10755 is a fungal metabolite that has been found in P. macrospinosa and has anticancer activity. It is cytotoxic to A549, H116, PSN-1, and T98G cancer cells (IC50s = 4.6, 4, 2.2, and 7.7 µM, respectively).Formal Name:...
Keywords: | 3a,4,5,6,6a,9,9a,9b-octahydro-3a-hydroxy-2-(hydroxymethyl)-5,8,9a-trimethyl-9-(1-methyl-1-propen-1-yl)-1H -phenalen-1-one |
Application: | Fungal metabolite, Antineoplastic |
CAS | 1262489-36-0 |
MW: | 330.5 D |
261.00€
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Item number: Cay15077-250
1,2-Dimyristoyl-sn-glycerol (1,2-DMG) is a saturated diacylglycerol (DAG) with myristic acid (14:0) side-chains attached at both the sn-1 and sn-2 positions. Most saturated DAGs, including 1,2-DMG, are weak second messengers for the activation of the PKC.Formal Name: tetradecanoic acid,...
Keywords: | 1,2-DMG, 1,1'-[(1S)-1-(hydroxymethyl)-1,2-ethanediyl] ester-tetradecanoic acid |
Application: | DAG |
CAS | 60562-16-5 |
MW: | 512.8 D |
From 65.00€
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Item number: Cay20757-25
Maresin 2-d5 (MaR2-d5) contains 5 deuterium atoms at the 21, 21, 22, 22, and 22 positions. It is intended for use as an internal standard for the quantification of MaR2 (Cay-16369) by GC- or LC-MS. MaR2 is a 13R,14S-dihydroxy DHA formed by recombinant human macrophage 12-lipoxygenase and soluble epoxide hydrolase...
Keywords: | 13R,14S-diHDHA-d5, 13R,14S-dihydroxy Docosahexaenoic Acid-d5, MaR2-d5,... |
Application: | Internal standard, GC, LC-MS |
MW: | 365.5 D |
From 226.00€
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