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Item number: Cay17292-10

NPPB is a chloride channel blocker (IC50 = 80 nM) that has also been identified as a GPR35 agonist. It has been shown to activate the GPR35-Galphai/o and GPR35-Galpha16 pathways in HEK293 cells, inducing intracellular calcium mobilization. NPPB has protonophoric activity and has been used to uncouple mitochondrial...

Keywords:	HOE 144, Hoechst 144, 5-nitro-2-[(3-phenylpropyl)amino]-benzoic acid
Application:	GPR35 agonist, chloride channel blocker
CAS	107254-86-4
MW:	300.3 D

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