N-(alpha-Linolenoyl) Tyrosine

N-(alpha-Linolenoyl) Tyrosine
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10032-5 5 mg -

6 - 10 business days*

96.00€
Cay10032-10 10 mg -

6 - 10 business days*

179.00€
Cay10032-50 50 mg -

6 - 10 business days*

742.00€
Cay10032-100 100 mg -

6 - 10 business days*

1,296.00€
 
Certain chronic neurologic disorders, such as Parkinson's disease, are caused by an insufficiency... more
Product information "N-(alpha-Linolenoyl) Tyrosine"
Certain chronic neurologic disorders, such as Parkinson's disease, are caused by an insufficiency of the neurotransmitter dopamine secondary to the degeneration of substantia nigra dopaminergic neurons. N-(alpha-Linolenoyl) tyrosine (NALT) is a simple alpha-amide conjugate between the omega-3 essential fatty acid alpha-linolenate and the amino acid tyrosine. alpha-Linolenate is an important precursor to docosahexaenoic acid (DHA), a prominent brain polyunsaturated fatty acid, while tyrosine is the metabolic precursor for neuronal dopamine synthesis. NALT was prepared as a method for enhancing central nervous system (CNS) dopamine content by facilitated transport of the tyrosine precursor across the blood-brain barrier. In experimental rat models of dopamine insufficiency, NALT increased CNS dopamine levels and exhibited an activity profile consistent with an anti-Parkinson's therapeutic agent.Formal Name: N-[(9Z,12Z,15Z)-1-oxo-9,12,15-octadecatrien-1-yl]-L-tyrosine. CAS Number: 259143-19-6. Synonyms: NALT. Molecular Formula: C27H39NO4. Formula Weight: 441.6. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): 1 mg/ml. lambdamax: 226, 278 nm. SMILES: CC/C=C\C/C=C\C/C=C\CCCCCCCC(N([C@H](C(O)=O)CC1=CC=C(O)C=C1)[H])=O. InChi Code: InChI=1S/C27H39NO4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-26(30)28-25(27(31)32)22-23-18-20-24(29)21-19-23/h3-4,6-7,9-10,18-21,25,29H,2,5,8,11-17,22H2,1H3,(H,28,30)(H,31,32)/b4-3-,7-6-,10-9-. InChi Key: DEQLZTQITSWABQ-PDBXOOCHSA-N.
Keywords: NALT, N-(L-tyrosine)-9Z,12Z,15Z-octadecatrienamide
Supplier: Cayman Chemical
Supplier-Nr: 10032

Properties

Application: Increases CNS dopamine levels
MW: 441.6 D
Formula: C27H39NO4
Purity: >98%
Format: Solution

Database Information

CAS : 259143-19-6| Matching products

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+P361+P353, P370+P378, P403+P235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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