N-Benzylacetamidine (hydrobromide)

Of the different types of nitric oxide synthases (NOS), the inducible (iNOS) form contributes to inflammation and immune response while the constitutively-expressed endothelial (eNOS) enzyme plays important roles in regulating vascular tone. N-Benzylacetamidine is a potent inhibitor of iNOS (IC50 = 0.20 µM), with over 1,000-fold selectivity compared to eNOS (IC50 = 350 µM).Formal Name: N-(phenylmethyl)-ethanimidamide, monohydrobromide. CAS Number: 186545-76-6. Molecular Formula: C9H12N2 . HBr. Formula Weight: 229.1. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 15 mg/ml, Ethanol: 25 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: CC(NCC1=CC=CC=C1)=N.Br. InChi Code: InChI=1S/C9H12N2.BrH/c1-8(10)11-7-9-5-3-2-4-6-9,/h2-6H,7H2,1H3,(H2,10,11),1H. InChi Key: RUQJDXJQOUUQHG-UHFFFAOYSA-N.