5 products were found matching "Cay13570"!
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N-Benzylacetamidine (hydrobromide)
Item number: Cay13570-10
Of the different types of nitric oxide synthases (NOS), the inducible (iNOS) form contributes to inflammation and immune response while the constitutively-expressed endothelial (eNOS) enzyme plays important roles in regulating vascular tone. N-Benzylacetamidine is a potent inhibitor of iNOS (IC50 = 0.20 µM), with...
| Keywords: | N-(phenylmethyl)-ethanimidamide, monohydrobromide |
| Application: | iNOS inhibitor |
| CAS | 186545-76-6 |
| MW: | 229.1 D |
From 88.00€
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Salinomycin
Item number: Cay13579-50
Cancer stems cells (CSCs) are a subpopulation of cells within tumors that drive tumor growth and recurrence. They are resistant to many current cancer treatments. Salinomycin (sodium salt) is an antibacterial and coccidiostat compound that shows selective toxicity for the CSCs that exist as a subpopulation within...
| Keywords: | alpha-ethyl-6-[5-[2-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[... |
| Application: | Tumor growth inhibitor, Antiprotozoal, Coccidiostat |
| CAS | 53003-10-4 |
| MW: | 751 D |
From 34.00€
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YM-201636
Item number: Cay13576-10
PIKfyve is a phosphoinositide kinase (PIK) that contains a FYVE-type zinc finger domain, which binds phosphatidylinositol 3-phosphate (PI3P). PIKfyve phosphorylates PI3P to produce PI-(3,5)-P2, which is involved in cellular processes including membrane trafficking and cytoskeletal reorganization. YM-201636 is a...
| Keywords: | 6-amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide |
| Application: | PIKfyve inhibitor |
| CAS | 371942-69-7 |
| MW: | 467.5 D |
From 68.00€
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3-bromo-5-phenyl Salicylic Acid
Item number: Cay13574-10
The aldo-keto reductase (AKR) enzymes constitute a family of related NADPH-dependent oxidoreductases. The 1C subfamily (AKR1C) includes four human hydroxysteroid dehydrogenases, with AKR1C1 being a 20alpha-HSD and the other three being 3alpha-HSDs. AKR1C1 metabolizes progesterone to an inactive progestin,...
| Keywords: | NSC 109116, 5-bromo-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid |
| Application: | AKR1C1 inhibitor |
| CAS | 4906-68-7 |
| MW: | 293.1 D |
From 86.00€
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VEGFR2 Kinase Inhibitor I
Item number: Cay13578-10
Vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR and FLK1) is a receptor tyrosine kinase that regulates angiogenesis, vascular development, and embryonic hematopoiesis in response to VEGF isoforms A, C, and D. VEGFR2 kinase inhibitor I is a potent, cell-permeable inhibitor of mouse VEGFR2...
| Keywords: | SU 5408, 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid, ethyl ester |
| Application: | Mouse VEGFR2 inhibitor |
| CAS | 15966-93-5 |
| MW: | 310.4 D |
From 92.00€
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