7 products were found matching "Cay10006438-2"!
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CAY10485
Item number: Cay10006482-5
Acyl-coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10485 inhibits human ACAT-1 and ACAT-2 with an IC50 values of 95 and 81 µM,...
| Keywords: | 3,4-dihydroxy Hydrocinnamic acid (L-Aspartic acid dibenzyl ester) amide,... |
| Application: | acylCoA inhibitor |
| CAS | 615264-62-5 |
| MW: | 477.5 D |
From 48.00€
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DMPO
Item number: Cay10006436-500
Free radicals are highly reactive, short-lived species. Spin traps react with radicals, forming stable adducts that can be further studied. DMPO is a commonly-used spin trap that reacts with O-, N-, S-, and C-centered radicals. This allows their characterization when used in association with electron spin resonance...
| Keywords: | 5,5-Dimethyl-1-Pyrroline-N-Oxide, 3,4-dihydro-2,3-dimethyl-2H-pyrrole 1-oxide |
| Application: | Spin trap |
| CAS | 3317-61-1 |
| MW: | 113.2 D |
From 84.00€
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Sulindac
Item number: Cay10004386-1000
Sulindac is a non-steroidal anti-inflammatory drug (NSAID), a COX-2 inhibitor (IC50 = 0.79 µM), and a prodrug form of the COX inhibitor sulindac sulfide (Cay-10004387). It is selective for COX-2 over COX-1 (IC50 = >1,000 µM). It inhibits acetic acid-induced writhing in mice and reduces carrageenan-induced paw edema...
| Keywords: | 5-fluoro-2-methyl-1Z-[[4-(methylsulfinyl)phenyl]methylene]-1H-indene-3-acetic acid |
| Application: | COX inhibitor |
| CAS | 38194-50-2 |
| MW: | 356.4 D |
From 19.00€
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DEPMPO
Item number: Cay10006435-50
DEPMPO is a phosphorylated derivative of the widely used DMPO spin trap. It has been reported to produce spin adducts with increased stability particularly for the adduct of superoxide. DEPMPO displays a detectable spin adduct signal at a concentration as low as 1 mM, as compared to 5 mM for DMPO (Cay-10006436). A...
| Keywords: | 5-(Diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide, P-(3,4-dihydro-2-methyl-1-oxido-2H-pyrrol-2-yl)-phosphonic acid,... |
| Application: | Spin trap |
| CAS | 157230-67-6 |
| MW: | 235.2 D |
From 163.00€
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Prostaglandin F2alpha-d9
Item number: Cay10008643-25
Prostaglandin F2alpha-d9 (PGF2alpha-d9) is intended for use as an internal standard for the quantification of PGF2alpha (Cay-16010) by GC- or LC-ms. PGF2alpha is a widely distributed PG occurring in many species. It causes contraction of vascular, bronchial, intestinal, and myometrial smooth muscle, and also...
| Keywords: | Dinoprost-d9, 9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-oic-17,17,18,18,19,19,20,20,20-d9 acid |
| Application: | Standard |
| MW: | 363.5 D |
From 65.00€
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Anti-Goat Anti-COX-2 (human) Affinity-Purified
Item number: Cay100034-1
Cyclooxygenase 2 (COX-2) is a bifunctional enzyme that exhibits both COX and peroxidase activities and catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins. The COX component converts arachidonic acid to the hydroperoxy endoperoxide prostaglandin G2 (PGG2, Cay-17010), and...
| Keywords: | Cyclooxygenase-2, PGHS-2, Prostaglandin H Synthase-2 |
| Application: | IF, IHC, WB |
| Host: | Goat |
| Species reactivity: | human, ovine, murine, rat |
422.00€
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FTY720 (S)-Phosphate
Item number: Cay10006408-1
FTY720 is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 is phosphorylated by sphingosine kinases in vivo, and then acts as a potent agonist at four of the five sphingosine-1-phosphate (S1P) receptors. FTY720...
| Keywords: | (S)-FTY 720P, (2S)-amino-2-[2-(4-octylphenyl)ethyl]-1-(dihydrogen phosphate)-1,3-propanediol |
| Application: | Metabolic studies |
| CAS | 402616-26-6 |
| MW: | 387.5 D |
From 94.00€
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