This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins...

Aminooxy-5(6)-TAMRA reacts with aldehydes or ketones to form a stable oxime compound under mild condition. Similar to ARP, aminooxy-5(6)-TAMRA can be used to label abasic sites in damaged DNA. It can also be used to label polysaccharides and glycoproteins.&lamba,Ex/&lamba, Em(MeOH) = 540/565 nmDark red solid soluble...

Exodus-2 is expressed in the HEV and T cell rich areas of lymph nodes and Peyer's patches, T cell areas of the spleen and by lymphatic endothelium of many organs, acting as a potent chemoattractant for thymocytes and T lymphocytes. Exodus-2 possesses characteristics of a homing molecule for lymphocytes to secondary...

SLC (secondary lymphoid-tissue chemokine, also called 6Ckine, TCA4, Exodus-2) is a 111aa (human, 110aa for mouse) CC chemokine with an NH2-terminal sequence of 23 residues as a signal sequence. It was originally cloned in 1997. Recombinant SLC attracts T-, B- cells, mature dendritic cell, but did not induce any cell...

Source: , Recombinant corresponding to 110aa from mouse Exodus 2 expressed in E. coli. Molecular Weight: ~12kD, Activity: The biological activity was determined by measuring dose-dependent chemotaxis with a total murine T cell population. A concentration range of 10-100ng/ml produced significant chemotaxis. 6 Ckine...