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Mildronate (hydrate)
Mildronate (hydrate)

Item number: Cay15997-25

Mildronate is a structural analog of gamma-butyrobetaine (gammaBB), an intermediate in the biosynthesis of carnitine. It blocks carnitine synthesis by inhibiting gammaBB hydroxylase (IC50 = 62 µM) and, less potently, carnitine acetyltransferase (Ki = 1.6 mM). Through these actions, mildronate reduces the levels of...
Keywords: Meldonium, MET-88, Quaterine, THP, 2-(2-carboxyethyl)-1,1,1-trimethyl-hydrazinium inner salt, dihydrate
Application: gamma-butyrobetaine dioxygenase inhibitor, carnitine synthesis inhibitor
CAS 86426-17-7
MW: 182.2 D
From 46.00€ *
Review
Everolimus
Everolimus

Item number: Cay11597-5

The mammalian target of rapamycin (mTOR) is a serine/threonine kinase that, as part of two distinct complexes (mTORC1 and mTORC2), plays pivotal roles in intracellular signaling. Everolimus is a hydroxyethyl ether rapamycin (Cay-13346) derivative that inhibits mTOR signaling through both mTORC1 and mTORC2 when added...
Keywords: RAD001, 42-O-(2-hydroxyethyl)-rapamycin
Application: mTOR inhibitor
CAS 159351-69-6
MW: 958.2 D
From 66.00€ *
Review
(±)-Salsolinol (hydrochloride)
(±)-Salsolinol (hydrochloride)

Item number: Cay15597-100

(±)-Salsolinol is a metabolite of ethanol produced by the condensation of dopamine with acetaldehyde in the brain. It is thought to contribute to some aspects of alcohol's addictive properties in part through its ability to stimulate dopamineric neurons in the posterior ventral tegmental area of the brain. At 0.1...
Keywords: 1,2,3,4-tetrahydro-1-methyl-6,7-isoquinolinediol, monohydrochloride
Application: Dopamine ethanol metabolite
CAS 79923-51-6
MW: 215.7 D
From 66.00€ *
Review