- Search results for Cay16665
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13 products were found matching "Cay16665"!
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Item number: Cay16665-50
Melphalan is a phenylalanine derivative of mechlorethamine, belonging to the family of nitrogen mustard alkylating agents that are used for chemotherapy. It attaches an alkyl group to guanine bases in DNA at the 7-nitrogen of the imidazole ring, which leads to DNA interstrand and intrastrand crosslinks,...
Keywords: | Alanine Nitrogen Mustard, Alkeran, L-Phenylalanine Mustard, NSC 241286, NSC 8806, 4-[bis(2-chloroethyl)amino]-L-phenylalanine |
Application: | Alkylating agent |
CAS | 148-82-3 |
MW: | 305.2 D |
From 109.00€
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Item number: Cay11166-5
5-Azacytidine is an analog of cytidine which can be incorporated into DNA, inhibit DNA methyltransferases, and cause hypomethylation of cytosine residues in the absence of any significant mutagenic effects. Decitabine is a 2'-deoxy analog of 5-azacytidine which similarly causes hypomethylation of DNA by inhibiting...
Keywords: | 5-aza-2'-Deoxycytidine, DAC, NSC 127716, 4-amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one |
Application: | Cytidine analog |
CAS | 2353-33-5 |
MW: | 228.2 D |
From 64.00€
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Item number: Cay11666-5
Methedrone (4-methoxymethcathinone) is a substituted cathinone with psychoactive actions. Its use as a recreational drug and its toxicity have recently been reported. 4-methyl-N,N-DMC is an analog of methedrone, differing by the presence of a second aminomethyl group. Its biological and toxicological properties have...
Keywords: | 4-methyl-N,N-DMC, N-Methylmethedrone, 2-(dimethylamino)-1-(4-methoxyphenyl)-1-propanone, monohydrochloride |
Application: | Analytical reference standard, Psychoactive substituted cathinone |
CAS | 1089307-23-2 |
MW: | 243.7 D |
From 266.00€
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Item number: Cay11655-25
Cannabipiperidiethanone (Cay-11655) is a synthetic cannabinoid (CB) with structural similarities to JWH 250 (Cay-13634) and AM2233 (Cay-11008) that has been identified as a component of "herbal" blends illegally sold in Japan. Cannabipiperidiethanone binds to the CB receptors CB1 and CB2 with IC50 values of 591 and...
Keywords: | 2-(2-methoxyphenyl)-1-[1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl]-ethanone |
Application: | Analytical reference standard, synthetic cannabinoid (CB1 / CB2 binding) |
CAS | 1345970-43-5 |
MW: | 376.5 D |
From 276.00€
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Item number: Cay11165-10
SGI-1027 is an inhibitor of the DNA methyltransferases DNMT1, DNMT3A, and DNMT3B (IC50s = 12.5, 8, and 7.5 µM, respectively, with Poly(dI-dC) as the substrate). It has been shown to cause the degradation of DNMT1 and to reactivate silenced tumor suppressor genes by reducing CpG island hypermethylation.Formal Name:...
Keywords: | DNA Methyltransferase Inhibitor II, N-[4-[(2-amino-6-methyl-4-pyrimidinyl)amino]phenyl]-4-(4-quinolinylamino)-benzamide |
Application: | DNMT1 / DNMT3A / DNMT3B inhibitor |
CAS | 1020149-73-8 |
MW: | 461.5 D |
From 50.00€
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Item number: Cay16655-100
Goat anti-Rabbit IgG conjugated to SureLight(TM) R-PE Antibody: Goat polyclonal anti-Rabbit IgG (minimally reactive toward mouse, bovine serum proteins) Dye: SureLight(TM) R-phycoerythrin (R-PE) Excitation max. lambda: 565>498 nm Emission max. lambda: 578 nm Uses: Flow cytometry, fluorescence-activated cell sorting,...
Application: | Cell based assays, FC |
Host: | Goat |
Species reactivity: | rabbit |
From 148.00€
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Item number: Cay16667-5
BMS 345541 is a cell permeable inhibitor of the IkappaB kinases IKKalpha and IKKbeta (IC50s = 4 and 0.3 µM). It is without effect against a panel of other serine/threonine and tyrosine kinases at 100 µM. BMS 345541 inhibits signaling through nuclear factor-kappaB (NF-kappaB) both in cells and in vivo, showing...
Keywords: | IKK Inhibitor III, N1-(1,8-dimethylimidazo[1,2-a]quinoxalin-4-yl)-1,2-ethanediamine, bis(2,2,2-trifluoroacetate) |
Application: | Cell permeable IKK-alpha/beta inhibitor |
CAS | 547757-23-3 |
MW: | 291.8 D |
From 60.00€
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Item number: Cay16669-5
2-Amino-5-fluorobenzoic acid is a toxic antimetabolite for the tryptophan pathway in yeast that can be used to counterselect for TRP1, a commonly used genetic marker in S. cerevisiae. Because this trp1 strain lacks the enzymes required for the conversion of anthranilic acid to tryptophan, it is resistant to...
Keywords: | 5-FAA, 5-Fluoroanthranilic Acid, NSC 513308, 2-amino-5-fluoro-benzoic acid |
Application: | Positive TRP1 yeast genetic marker selection |
CAS | 446-08-2 |
MW: | 155.1 D |
From 66.00€
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Item number: Cay16660-5
13,14-dihydro Prostaglandin F2alpha (13,14-dihydro PGF2alpha) is the analog of PGF2alpha which has no unsaturation in the lower side chain. It causes luteolysis in hamsters with a potency five times higher than PGF2alpha. The ED50 value for 13,14-dihydro PGF2alpha as a luteolytic agent in hamsters is 1.5 µg/100...
Keywords: | 13,14-dihydro PGF2alpha, 9alpha,11alpha,15S-trihydroxy-prost-5Z-en-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 27376-74-5 |
MW: | 356.5 D |
From 66.00€
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Item number: Cay16663-5
Chlortetracycline is an analog of tetracycline (Cay-14328), a broad spectrum antibiotic. In addition to its actions against microorganisms, chlortetracycline suppresses inflammation by inhibiting neutrophil action and other aspects of the innate immune response. 4-epi-Chlortetracycline is an epimer of...
Keywords: | 7-chloro-2-Naphthacenecarboxamide,... |
Application: | Antibiotic, Innate immune response suppressor |
CAS | 101342-45-4 |
MW: | 515.3 D |
From 125.00€
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Item number: Cay16664-5
Mozavaptan is an orally bioavailable antagonist of vasopressin V2 receptors (Ki = 9.42 nM in HeLa cells expressing the human receptor). It is selective for vasopressin V2 over V1 receptors (IC50s = 14 and 1,200 nM, respectively) in radioligand binding assays using rat kidney and rat liver membranes that endogenously...
Keywords: | OPC 31260, N-[4-[[5-(dimethylamino)-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl]phenyl]-2-methyl-benzamide,... |
Application: | Arginine vasopressin receptor 2 (AVPR2) antagonist |
CAS | 138470-70-9 |
MW: | 464 D |
From 48.00€
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Item number: Cay16668-5
The kinesin-like spindle protein Eg5, also known as KSP and Kif11, is a motor protein that is essential for establishing a bipolar spindle during mitosis. Eg5-I is a potent inhibitor of Eg5, both in vitro and in cells (IC50s = 127 and 190 nM, respectively). It is an analog of S-trityl-L-cysteine (STLC), but is more...
Keywords: | (2R)-2-amino-3-[[(4-methoxyphenyl)diphenylmethyl]thio]-1-propanol |
Application: | Eg5 inhibitor |
CAS | 1338701-15-7 |
MW: | 379.5 D |
From 66.00€
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