Maslinic Acid

Maslinic Acid
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10009645-1 1 mg -

6 - 10 business days*

42.00€
Cay10009645-5 5 mg -

6 - 10 business days*

141.00€
Cay10009645-10 10 mg -

6 - 10 business days*

255.00€
Cay10009645-25 25 mg -

6 - 10 business days*

586.00€
 
Maslinic acid is found in a number of natural sources, most notably pomace olive oil (orujo).... more
Product information "Maslinic Acid"
Maslinic acid is found in a number of natural sources, most notably pomace olive oil (orujo). This pentacyclic triterpene has an antiproliferative effect against Caco-2 cancer cells (EC50 = 15 µM), HT-29 human colon cancer cells (EC50 = 74 µM), 1321N1 astrocytoma cells (IC50 = 25 µM), and human leukemia (CCRF-CEM and CEM/ADR5000) cells (IC50 = 7 µM and 9 µM respectively).{15043, 15044, 15046, 15045} Maslinic acid's antiproliferative activity likely comes from the induction of an oxidative apoptotic pathway, causing cell cycle and cytoskeleton alterations. Maslinic acid has been found to attenuate intracellular oxidative stress via inhibition of NO and H2O2 production and reduction of pro-inflammatory cytokine generation in murine macrophages. Recently maslinic acid has been found to inhibit the spread of the HIV virus by inhibiting the replication of a primary HIV-1 isolate as well as decreased the cytopathic effect and p24 antigen levels in MT2 cells.Formal Name: 2alpha,3beta-dihydroxy-olean-12-en-28-oic acid. CAS Number: 4373-41-5. Synonyms: Crategolic Acid, 2alpha-Hydroxyoleanoic Acid. Molecular Formula: C30H48O4. Formula Weight: 472.7. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 15 mg/ml, DMSO: 20 mg/ml, DMSO: PBS (pH 7.2)(1:2): 0.3 mg/ml, Ethanol: 0.5 mg/ml. SMILES: CC1(C)CC[C@]2(C(O)=O)CC[C@@]3(C)[C@]4(C)CCC5C(C)(C)[C@@H](O)[C@H](O)C[C@]5(C)[C@@]4([H])CC=C3[C@@]2([H])C1. InChi Code: InChI=1S/C30H48O4/c1-25(2)12-14-30(24(33)34)15-13-28(6)18(19(30)16-25)8-9-22-27(5)17-20(31)23(32)26(3,4)21(27)10-11-29(22,28)7/h8,19-23,31-32H,9-17H2,1-7H3,(H,33,34)/t19-,20-,21?,22-,23+,27+,28-,29-,30?/m1/s1. InChi Key: MDZKJHQSJHYOHJ-UKSPDLIDSA-N.
Keywords: 2alpha-Hydroxyoleanoic Acid, Crategolic Acid, 2alpha,3beta-dihydroxy-olean-12-en-28-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 10009645

Properties

Application: NO production inhibitor
MW: 472.7 D
Formula: C30H48O4
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 4373-41-5| Matching products

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Maslinic Acid"
Write a review
or to review a product.
Viewed