7 products were found matching "Cay10009645"!

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Maslinic Acid
Maslinic Acid

Item number: Cay10009645-5

Maslinic acid is found in a number of natural sources, most notably pomace olive oil (orujo). This pentacyclic triterpene has an antiproliferative effect against Caco-2 cancer cells (EC50 = 15 µM), HT-29 human colon cancer cells (EC50 = 74 µM), 1321N1 astrocytoma cells (IC50 = 25 µM), and human leukemia (CCRF-CEM...
Keywords: 2alpha-Hydroxyoleanoic Acid, Crategolic Acid, 2alpha,3beta-dihydroxy-olean-12-en-28-oic acid
Application: NO production inhibitor
CAS 4373-41-5
MW: 472.7 D
From 42.00€ *
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Eicosapentaenoyl Ethanolamide
Eicosapentaenoyl Ethanolamide

Item number: Cay10964-5

Eicosapentaenoyl ethanolamide (EPEA) is an N-acylethanolamide that inhibits dietary-restriction-induced lifespan extension in wild type and TOR pathway mutant nematodes. Produced endogenously from eicosapentaenoic acid, EPEA serves as a metabolic signal that couples nutrient availability with growth and lifespan....
Keywords: EPEA, N-(2-hydroxyethyl)-5Z,8Z,11Z,14Z,17Z-eicosapentaenamide
Application: Bioactive Lipid Assays
CAS 109001-03-8
MW: 345.5 D
From 84.00€ *
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Sorafenib
Sorafenib

Item number: Cay10009644-5

Sorafenib is a multi-kinase inhibitor that inhibits Raf-1 and B-RAF (IC50s = 6 and 22 µM, respectively), as well as the receptor tyrosine kinases VEGFR2, VEGFR3, PDGFRbeta, FLT3, and c-Kit (IC50s = 90, 15, 20, 57, and 58 nM, respectively). It is selective for these kinases over 12 other kinases, including ERK1,...
Keywords: BAY 43-9006, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide
Application: Kinase inhibitor
CAS 284461-73-0
MW: 464.8 D
From 43.00€ *
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SOTS-1 (technical grade)
SOTS-1 (technical grade)

Item number: Cay10009642-5

Superoxide radical anion is a toxic by-product of mitochondrial respiration that is formed from approximately 1-4% of the oxygen metabolized by aerobic organisms. SOTS-1 is an azo-compound that can be thermally decomposed in aqueous solution to generate superoxide radical anion at a constant, controlled rate. More...
Keywords: Di-(4-Carboxybenzyl)Hyponitrite, Superoxide Thermal Source, 4,4'-[azobis(oxymethylene]bis-benzoic acid
Application: Superoxide effect studies
CAS 223507-96-8
MW: 330.3 D
From 43.00€ *
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Purmorphamine
Purmorphamine

Item number: Cay10009634-5

Small molecules that promote osteoblast differentiation might be useful as therapeutic agents for bone diseases such as osteoporosis. Purmorphamine is a 2,6,9-trisubstituted purine that promotes the differentiation of both human and mouse mesenchymal progenitor cells into osteoblasts. The EC50 value for...
Keywords: 9-cyclohexyl-N-[4-(morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine
Application: Differentiation promotor
CAS 483367-10-8
MW: 520.6 D
From 39.00€ *
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1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PC
1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PC

Item number: Cay10009864-5

1-Stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC) is a phospholipid containing stearic acid (Cay-10011298) and arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) at the sn-1 and sn-2 positions, respectively. It is a component of LDL and has been found in human stenotic aortic valves and atherosclerotic plaques....
Keywords: 18:0/20:4-PC, 1-Stearoyl-2-Arachidonoyl-sn-glycero-3-Phosphatidylcholine,...
Application: Bioactive lipid assays
CAS 35418-59-8
MW: 810.1 D
From 109.00€ *
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COVID-19 Research
E-64c
E-64c

Item number: Cay10007964-5

E-64c is an active metabolite of the protease inhibitor E-64d (Cay-13533). E-64c inhibits the cysteine proteases cathepsin B, cathepsin H, and papain but not the serine proteases trypsin, chymotrypsin, or elastase. It reduces the autocatalytic activity of the foot-and-mouth-disease virus (FMDV) leader protease when...
Keywords: Loxistatin Acid, NSC 694279,...
Application: Cysteine protease inhibitor
CAS 76684-89-4
MW: 314.4 D
From 84.00€ *
Review