- Search results for 401
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46 products were found matching "401"!
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Item number: ABD-401
Molecular weight: 1030.23. Excitation (nm): 578. Emission (nm): 595. Although ROX dyes have strong fluorescence they are notoriously unstable. Some commercial samples only have a few months' shelf life. Compared to 6-ROX labeling compounds our 6-ROXtra(TM) dyes have greatly enhanced stability while they have...
Application: | Stable, water-soluble ROX replacement, 5'-amine-modified oligonucleotide labelling |
MW: | 1030.23 D |
124.00€
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Item number: Cay20393-25
TCS 401 is a selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B, Ki = 0.29 µM). It inhibits the protein phosphatases CD45 D1D2, PTPbeta, PTPepsilon D1, SHP-1, PTPalpha D1, and LAR D1D2 at much higher concentrations (Kis = 59, 560, 1,100, >2,000, >2,000, and >2,000 µM, respectively). Several PTPs have been...
Keywords: | 2-[(carboxycarbonyl)amino]-4,5,6,7-tetrahydro-thieno[2,3-c]pyridine-3-carboxylic acid, monohydrochloride |
Application: | Selective PTP1B inhibitor |
CAS | 243966-09-8 |
MW: | 306.7 D |
From 44.00€
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Item number: Cay21769-1
Compound 401 is an inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR, IC50s = 0.28 and 5.3 µM, respectively). It is selective for DNA-PK and mTOR over PI3K, ATM, and ATR (IC50s = >100 µM for all). Compound 401 (10 µM) inhibits phosphorylation of the mTOR targets S6K1 and Akt...
Keywords: | 2-(4-morpholinyl)-4H-pyrimido[2,1-a]isoquinolin-4-one |
Application: | DNA-PK / FRAP inhibitor |
CAS | 168425-64-7 |
MW: | 281.3 D |
From 43.00€
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Item number: LKT-P0276.500
Antimicrobial peptide found in bee and wasp venom.
Keywords: | Mast Cell Degranulating Peptide |
Application: | Antimicrobial peptide found in bee and wasp venom |
CAS | 32908-73-9 |
MW: | 2583.28 D |
From 468.00€
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Item number: Cay81035-5
CDDO is a synthetic oleanane triterpenoid that blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-gamma-activated mouse macrophages with an IC50 value of 0.4 nM. By suppressing reactive oxygen and nitrogen species (ROS/RNS) formation, it promotes the cellular control of...
Keywords: | Bardoxolone, RTA 401, 2-cyano-3,12-dioxo-oleana-1,9(11)-dien-28-oic acid |
Application: | PPAR gamma ligand |
CAS | 218600-44-3 |
MW: | 491.7 D |
From 84.00€
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Item number: Cay30288-250
Clorsulon is a sulfonamide antiparasitic agent. It induces swelling and blebbing and reduces motility of F. hepatica mature flukes when used at a concentration of 10 µg/ml. In vivo, clorsulon (3.5-15 mg/kg) reduces the number of flukes in a goat model of F. hepatica infection. It completely eradicates naturally...
Keywords: | L-631529, MK 401, 4-amino-6-(1,2,2-trichloroethenyl)-1,3-benzenedisulfonamide |
Application: | Sulfonamide antiparasitic agent, Fasciolicide |
CAS | 60200-06-8 |
MW: | 380.7 D |
From 84.00€
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Item number: Cay27112-100
Amyloid-beta (40-1) peptide (Abeta (40-1)) is a peptide that contains the reverse sequence of Abeta (1-40) peptide (Cay-21617). Abeta (40-1) does not induce neurotoxicity of rat cortical neurons when administered via microinjection into the cerebral cortex at a dose of 3 nmol. It has been used as an inactive control...
Keywords: | Abeta (40-1),... |
Application: | Inactive control |
MW: | 4329.9 D |
245.00€
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Item number: RP2000AP-025
Produced in Yeast. Amino acid sequence: IKCNCKRHVI KPHICRKICG KNG (23).
Keywords: | MCDP, MCD peptide, Peptide 401, Mast cell degranulating peptide |
Application: | Bioassays |
Expressed in: | Yeast |
Origin: | bee |
MW: | 2.6 kD |
From 206.00€
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Item number: SYN-1028-M050
Soluble in DMSO. CC-401 is a competitive inhibitor of the ATP binding site in the active, phosphorylated, form of JNK. This prevents JNK from phosphorylating its various target molecules, including the amino terminus of c-Jun. It is a potent inhibitor of all three forms of JNK (Ki of 25-50 nM), and has at least...
Keywords: | CC401 |
Application: | JNK inhibitor |
CAS | 1438391-30-0 |
MW: | 424,9 D |
From 152.00€
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Item number: Cay18867-1
c-Jun N-terminal kinases (JNKs) are MAP kinase family members that become highly activated after cells are exposed to stress conditions and are poorly activated by exposure to growth factors or mitogens. CC-401 is a potent inhibitor of all three JNK isoforms (Ki values range from 25 to 50 nM). It has at least...
Keywords: | 3-[3-[2-(1-piperidinyl)ethoxy]phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-indazole |
Application: | JNK inhibitor |
CAS | 395104-30-0 |
MW: | 388.5 D |
From 142.00€
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Item number: Cay31108-5
LEI-401 is an inhibitor of N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD, IC50 = 0.86 µM in HEK293T cell membranes expressing the recombinant human enzyme). It is selective for NAPE-PLD over human cannabinoid (CB) receptor 1 (CB1), CB2, type IVE phospholipase A2, monoacylglycerol lipase (MAGL), and...
Keywords: | N-(cyclopropylmethyl)-6-[(3S)-3-hydroxy-1-pyrrolidinyl]-2-[(3S)-3-phenyl-1-piperidinyl]-4-pyrimidinecarboxamide |
Application: | NAPE-PLD inhibitor |
CAS | 2393840-15-6 |
MW: | 421.5 D |
From 158.00€
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Item number: Cay16898-10
JX-401 is a potent, reversible inhibitor of the p38alpha isoform of MAP kinase (IC50 = 32 nM). It does not inhibit the p38gamma isoform. JX-401 is effective in mammalian cells, as it blocks the differentiation of myoblasts into myotubes.Formal Name:...
Keywords: | p38 MAPK Inhibitor VI, p38 Mitogen-activated Protein Kinase Inhibitor VI,... |
Application: | p38alpha inhibitor |
CAS | 349087-34-9 |
MW: | 355.5 D |
From 77.00€
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