- Search results for 402
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33 products were found matching "402"!
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Item number: ABE-35-1511-50
The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through...
Keywords: | Anti-PAK-1, Anti-p65-PAK, Anti-Alpha-PAK, Anti-p21-activated kinase 1, Anti-Serine/threonine-protein kinase PAK 1,... |
Application: | IHC, WB, IF |
Host: | Rabbit |
Species reactivity: | rat, mouse, human |
574.00€
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Item number: ABE-35-1511-100
The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through...
Keywords: | Anti-PAK-1, Anti-p65-PAK, Anti-Alpha-PAK, Anti-p21-activated kinase 1, Anti-Serine/threonine-protein kinase PAK 1,... |
Application: | IHC, WB, IF |
Host: | Rabbit |
Species reactivity: | rat, mouse, human |
682.00€
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-10 %
Discount Promotion
Item number: ELK-ES6462.100
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member...
Keywords: | PAK1, Serine/threonine-protein kinase PAK 1, Alpha-PAK, p21-activated kinase 1, PAK-1, p65-PAK, PAK2,... |
Application: | WB, IHC, IF, ELISA |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
169.00€
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From 152.10€
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Item number: 224851.100
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 531.00€
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Item number: MON-MON3030
MON3030 reacts specific with the heavy component of the three subunits of neurofilaments. In immunoblots it reacts with the 200 kD protein. Neurofilaments, the interme-diate filaments of neurons, are composed of three polypeptides with a molecule weight of respectively, 70, 160 and 200 kD. The three polypeptides can...
Keywords: | Anti-NEFH, Anti-NF-H, Anti-KIAA0845, Anti-200 kDa neurofilament protein, Anti-Neurofilament triplet H protein,... |
Application: | IHC |
Host: | Mouse |
Species reactivity: | Bovine, Guinea pig, Human, Rat |
337.00€
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Item number: ABD-8B0540.50
Custom conjugation services for this antibody as available (eg. labeling of Anti-PAK1/2/3 (Ab-423/402/421) with HRP. Available labels are AF: AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750. Proteins: HRP, Alkaline Phosphatase, Streptavidin. Tandems: APC, APC/Cy7, APC/AF750, APC/iFluor(TM) 700, APC/iFluor(TM)...
Keywords: | Anti-PAK-1, Anti-p65-PAK, Anti-Alpha-PAK, Anti-p21-activated kinase 1, Anti-Serine/threonine-protein kinase PAK 1,... |
Application: | WB, IHC, ELISA |
Host: | Rabbit |
Species reactivity: | human, mouse |
601.00€
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Item number: ABD-8A0540.50
Custom conjugation services for this antibody as available (eg. labeling of Anti-phospho-PAK1/2/3 (Thr423/402/421) with HRP. Available labels are AF: AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750. Proteins: HRP, Alkaline Phosphatase, Streptavidin. Tandems: APC, APC/Cy7, APC/AF750, APC/iFluor(TM) 700,...
Keywords: | Anti-phospho-PAK-1, Anti-phospho-p65-PAK, Anti-phospho-Alpha-PAK, Anti-phospho-p21-activated kinase 1,... |
Application: | IHC, ELISA |
Host: | Rabbit |
Species reactivity: | human, mouse |
601.00€
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Item number: Cay11883-5
The synthetic oleanane triterpenoid CDDO (Cay-81035) is a Nrf2 activator that inhibits proliferation and induces differentiation and apoptosis in various cancer cells. The C-28 methyl ester of CDDO (CDDO methyl ester) blocks the cellular synthesis of inducible nitric oxide synthase (iNOS) and inducible COX-2 in...
Keywords: | Bardoxolone methyl, NSC 713200, RTA 402, TP-155, 2-cyano-3,12-dioxo-oleana-1,9(11)-dien-28-oic acid, methyl ester |
Application: | Apoptosis inducer |
CAS | 218600-53-4 |
MW: | 505.7 D |
From 74.00€
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Item number: LKT-P4132.5
PKI402 is an inhibitor of PI3K that is somewhat selective for p110 , it also inhibits mTORC1/2. PKI402 exhibits anticancer chemotherapeutic activity, inhibiting cell proliferation in vitro and suppressing tumor growth induced by a variety of cancer cells in vitro, such as breast cancer, glioma, and pancreatic cancer.
Application: | PI3K p110 / mTORC1/2 inhibitor |
CAS | 1173204-81-3 |
MW: | 570.65 D |
From 205.00€
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Item number: Cay27664-5
PKI-402 is a dual inhibitor of PI3K and mammalian target of rapamycin (mTOR, IC50s = 1.4, 9.2, and 1.7 nM for PI3Kalpha, PI3Kgamma, and mTOR, respectively). It reduces proliferation of MDA-MB-361 and PC3 cancer cells (IC50s = 8 and 21 nM, respectively) and inhibits phosphorylation of Akt in MDA-MB-361 cells (IC50 =...
Keywords: | N-[4-[3-ethyl-7-(4-morpholinyl)-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-yl]phenyl]-N'-[4-[(4-methyl-1-piperazinyl)carbonyl]phe... |
Application: | PI3K, mTOR dual inhibitor |
CAS | 1173204-81-3 |
MW: | 570.6 D |
From 77.00€
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Item number: ARG65217.100
Protein function: E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance. Binds to miRNAs and associates with AGO2, participating in post-transcriptional repression of transcripts such as CDKN1A. Facilitates the G1-S...
Keywords: | Anti-LIN41, Anti-TRIM71, EC=6.3.2.-, Anti-Protein lin-41 homolog, Anti-E3 ubiquitin-protein ligase TRIM71, Anti-Tripartite... |
Application: | ELISA, WB |
Host: | Goat |
Species reactivity: | human, mouse |
784.00€
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Item number: 100-401-402
Protein function: Binds and activates TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation. Plays an important role in the regulation of angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also...
Keywords: | Anti-Agpt, Anti-ANG-1, Anti-Angpt1, Anti-Angiopoietin-1 |
Application: | ELISA, IHC, IP, WB |
Host: | Rabbit |
Species reactivity: | mouse, human |
684.00€
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