Macrophage inflammatory protein 1-beta (MIP-1 beta, MIP-1b, CCL4, Chemokine (C-C motif) ligand 4, AC

Macrophage Inflammatory Protein-1( (MIP-1& alpha) is part of the CC subfamily of the chemokine superfamily of chemoattractant cytokines. MIP-1& alpha affects the inflammatory response of blood monocytes, tissue macrophages, and T cells. MIP-1& alpha also enhances the formation of granulocyte-macrophage colonies stimulated by GM-CSF or M-CSF. Human MIP-1& alpha is composed of 69 aa residues with one possible N-linked glycosylation sites, and several possible O-linked sites. Human MIP-1& alpha is 60% homologous with human MIP-1& alpha. Source: yeast, Biological Activity: The biological activity of recombinant human MIP-1&# alpha is determined by its use as a cofactor for CSF-dependent myelopoiesis. Storage and Stability: Lyophilized powder may be stored at -20°C. Reconstitute to with sterile dH2O or buffer, aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.