Macrophage Inflammatory protein-1 alpha (CCL3), His tag, mouse recombinant (rmMIP-1a-His)

Macrophage Inflammatory protein-1 alpha (CCL3), His tag, mouse recombinant (rmMIP-1a-His)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
97586.2 2 µg - -

3 - 10 business days*

94.00€
97586.10 10 µg - -

3 - 10 business days*

208.00€
97586.1 1 mg - -

3 - 10 business days*

7,571.00€
 
Mouse recombinant MIP-1a produced in E.coli is a single, non-glycosylated polypeptide chain... more
Product information "Macrophage Inflammatory protein-1 alpha (CCL3), His tag, mouse recombinant (rmMIP-1a-His)"
Mouse recombinant MIP-1a produced in E.coli is a single, non-glycosylated polypeptide chain containing 93 amino acids (24-92) and having a molecular mass of 10.4kDa. MIP-1a is fused to a 24 amino acid His-tag at N-terminus. Macrophage Inflammatory Proteins (MIP) belong to the family of chemotactic cytokines known as chemokines. In humans, there are two major forms, MIP-1a and MIP-1b that are now officially named CCL3 and CCL4 respectively. Both are major factors produced by macrophages after they are stimulated with bacterial endotoxins. They activate human granulocytes (neutrophils, eosinophils and basophils) which can lead to acute neutrophilic inflammation. They also induce the synthesis and release of other pro-inflammatory cytokines such as interleukin 1 (IL-1), IL-6 and TNF-a from fibroblasts and macrophages. The genes for CCL3 and CCL4 are both located on human chromosome 17.
Keywords: Ccl3, TY-5, Mip1a, L2G25B, SIS-alpha, MIP-1-alpha, C-C motif chemokine 3, Small-inducible cytokine A3, Heparin-binding chemotaxis protein, Macrophage inflammatory protein 1-alpha
Supplier: Biomol GmbH
Supplier-Nr: 97586

Properties

Application: Bioassays
Conjugate: No
Host: E.coli
Species reactivity: mouse
MW: 10400 D
Purity: >90%
Format: Solution

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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