Macrophage Inflammatory Protein-1 beta (CCL4), human recombinant (rHuMIP-1b)

Macrophage Inflammatory Protein-1 beta (CCL4), human recombinant (rHuMIP-1b)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
94845.2 2 µg - -

3 - 10 business days*

94.00€
94845.10 10 µg - -

3 - 10 business days*

208.00€
94845.1 1 mg - -

3 - 10 business days*

3,952.00€
 
Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major... more
Product information "Macrophage Inflammatory Protein-1 beta (CCL4), human recombinant (rHuMIP-1b)"
Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8 T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 69 amino acids. CCL3 and CCL4 are major factors produced by macrophages after they are stimulated with bacterial endotoxins.
Keywords: Small inducible cytokine A4, CCL4, Macrophage inflammatory protein 1-beta, MIP-1- beta, MIP-1-beta(1-69), T-cell activation protein 2, ACT-2, PAT 744, H400, SIS-gamma, Lymphocyte activation gene 1 protein, LAG-1, HC21, G-26 T-lymphocyte-secreted protein,
Supplier: Biomol GmbH
Supplier-Nr: 94845

Properties

Application: Chemoattract.
Conjugate: No
Host: E.coli
Species reactivity: human
MW: 7620.00 D
Format: Lyophilized

Database Information

KEGG ID : K12964 | Matching products
UniProt ID : P13236 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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