10 products were found matching "97535.1"!

Pelargonidin is an anthocyanidin that has been found in P. granatum and has diverse biological activities. It scavenges superoxide anions in cell-free assays (IC50 = 130 µg/ml) and inhibits hydrogen peroxide-induced lipid peroxidation in rat brain homogenates (IC50 = 85 µM). Pelargonidin (3 mg/kg) reduces serum...

CSL (CBF1/RBP-Jk, Su(H)/Suppressor of Hairless, Lag-1) is a 56kD member of the Su(H) family of transcription factors. It is constitutively bound to DNA where it participates in gene repression. Upon ligand binding, the intracellular domain of Notch translocates to the nucleus and interacts with CSL, allowing...

3,4-Methylenedioxy-alpha-methylaminohexanophenone (hydrochloride) (Cay-29753) is an analytical reference standard categorized as a cathinone. This product is intended for research and forensic applications.Formal Name: 1-(1,3-benzodioxol-5-yl)-2-(methylamino)-1-hexanone, monohydrochloride. CAS Number: 27912-40-9....

Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads...

Synthetic. Soluble in aqueous solution (5% AcOH) (1mg/ml). Glucagon-like peptide-1 (GLP-1) receptor agonist. Antidiabetic agent against type 2 diabetes (T2D). Stimulates insulin and suppresses glucagon secretion in a glucose-dependent manner. Longer-acting alternative to liraglutide. Chemically similar to...

10-Chloroestra-1,4-diene-3,17-dione is a sterone agonist of estrogen receptor alpha (ERalpha). It increases reporter gene expression in S. cerevisiae (EC50 = 0.36 nM for the human receptor). It also is an aromatase inhibitor (IC50 = 2.4 µM).Formal Name: 10-chloro-estra-1,4-diene-3,17-dione. CAS Number: 91413-55-7....

Solid lyophilized powder. Soluble in aqueous solution (5% AcOH) (1mg/ml). Chemical. CAS: 910463-68-2 (parent). Formula: C187H291N45O59 . C2H4O2. MW: 4113.6 . 60.0. Synthetic. Glucagon-like peptide-1 (GLP-1) receptor agonist. Antidiabetic agent against type 2 diabetes (T2D). Stimulates insulin and suppresses glucagon...

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

Lipid C-1 is an ionizable cationic amino lipid and a derivative of SM-102 (Cay-33474). It has been used in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro. LNPs containing lipid C-1 and encapsulating an mRNA reporter induce higher luciferase expression in Calu-3 cells than SM-102.Formal...

Roflumilast N-oxide is an inhibitor of phosphodiesterase 4 (PDE4, IC50 = 2 nM) and an active metabolite of the PDE4 inhibitor roflumilast (Cay-15141). It is selective for PDE4 over PDE1-3 and PDE5 (IC50s = >10,000 nM for all). It reduces TNF-alpha-induced ICAM-1 and eotaxin levels when used in combination with...