- Search results for Cay14961
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8 products were found matching "Cay14961"!
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Item number: Cay14961-10
Glutamate, the major excitatory neurotransmitter in the brain, acts on both ionotropic and metabotropic glutamate receptors. Excessive metabotropic glutamate receptor (mGluR) transmission has been linked to epilepsy, ischemia, pain, anxiety, and depression. Eight subtypes (1-8) and multiple splice variants of the...
Keywords: | 3-[2-(2-methyl-4-thiazolyl)ethynyl]-pyridine, monohydrochloride |
Application: | mGlu5a receptor antagonist |
CAS | 1186195-60-7 |
MW: | 236.7 D |
From 44.00€
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Item number: Cay14496-1
N-Phenylacetyl-L-prolylglycine ethyl ester is a synthetic dipeptide that has been shown to produce positive nootropic and cognitive effects in animal models (0.01-0.8 mg/kg) by a mechanism similar to other related racetam compounds. It can rescue neuroblastoma SH-SY5Y cells from amyloid-induced cytotoxicity,...
Keywords: | GVS-111, Noopept, SGS 111, 1-(2-phenylacetyl)-L-prolyl-glycine, ethyl ester |
Application: | Analytical reference standard, Synthetic dipeptide, Nootropic, Antioxidant, Antiinflammatory |
CAS | 157115-85-0 |
MW: | 318.4 D |
From 84.00€
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Item number: Cay14996-1
STA-21 is a natural antibiotic that potently inhibits STAT3 by preventing its dimerization and DNA binding when used at concentrations of 20-30 µM. It blocks the growth and survival of cancer cells that express constitutively active STAT3 (e.g., DU145 cells, IC50 = 12.2 µM). STAT3 inhibitors, including STA-21,...
Keywords: | Ochromycinone, (3S)-3,4-dihydro-8-hydroxy-3-methyl-benz[a]anthracene-1,7,12(2H)-trione |
Application: | STAT3 inhibitor |
CAS | 28882-53-3 |
MW: | 306.3 D |
From 163.00€
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Item number: Cay14965-1
Furin is a proprotein convertase, converting precursor proteins to functional proteins within the Golgi/trans-Golgi secretory pathway. Furin inhibitor I is a selective, irreversible, and cell-permeable competitive inhibitor of proprotein convertases, including furin/SPC1 (Ki = ~1 nM), SPC2/PC2 (Ki = 0.36 nM),...
Keywords: | Decanoyl-Arg-Val-Lys-Arg-CMK,... |
Application: | Proprotein convertase inhibitor, antiviral agent |
MW: | 744.4 D |
From 125.00€
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Item number: Cay14964-1
Tetrodotoxin (TTX) is a potent marine-derived neurotoxin that reversibly inhibits the inward sodium current through voltage-activated sodium (Nav) channels, blocking nerve and muscle action potentials. It inhibits the Nav current in frog muscle and squid axon with IC50 values of 4.1 and 5.2 nM, respectively, and...
Keywords: | TTX citrate,... |
Application: | NaV channel blocking |
CAS | 18660-81-6 |
MW: | 511.4 D |
340.00€
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Item number: Cay14969-1
Histone deacetylases (HDACs) catalyze the hydrolytic removal of acetyl groups from histone lysine residues, which commonly results in chromatin condensation and transcriptional repression. LMK 235 is an HDAC inhibitor that selectively targets HDACs 4 and 5 (IC50s = 12 and 4 nM, respectively) over other HDACs (IC50s...
Keywords: | N-[[6-(hydroxyamino)-6-oxohexyl]oxy]-3,5-dimethyl-benzamide |
Application: | HDAC4 inhibitor, HDAC5 inhibitor |
CAS | 1418033-25-6 |
MW: | 294.4 D |
From 50.00€
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Item number: Cay14963-1
TTX is a potent marine-derived neurotoxin that reversibly inhibits the inward sodium current through voltage-activated sodium (NaV) channels, blocking nerve and muscle action potentials. It inhibits the NaV current in frog muscle and squid axon with IC50 values of 4.1 and 5.2 nM, respectively, and binds to rat brain...
Keywords: | Araregai Toxin, Maculotoxin, Tectin, TTX,... |
Application: | NaV channel blocking |
CAS | 4368-28-9 |
MW: | 319.3 D |
310.00€
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Item number: Cay14960-1
Fluo-3 is a fluorescent calcium indicator commonly used in flow cytometry (FC) and cell-based experiments to detect changes in intracellular calcium levels. Its absorption maximum at 506 nm makes it compatible with excitation at 488 nm by argon-ion laser sources. Fluo-3 provides intense fluorescence upon binding...
Keywords: | Fluo-3 Acetoxymethyl ester,... |
Application: | FC, Fluorescent calcium indicator |
CAS | 121714-22-5 |
MW: | 1129.9 D |
From 196.00€
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