12 products were found matching "Cay15484"!

Ibotenic acid is a neuroexcitatory amino acid originally isolated from Amanita species that functions as a NMDA and metabotropic glutamate receptor agonist. As a neurotoxin, ibotenic acid is often used to induce brain lesions in animals that model cognitive dysfunctions resulting from neurodegenerative diseases,...

QX-314 is a membrane-impermeant lidocaine derivative that selectively blocks sodium channels on nociceptive neurons when delivered intracellularly via the TRPV1 channel, but is reportedly ineffective with extracellular application. When supplied in combination with 1 µM capsaicin (Cay-92350), a TRPV1 receptor...

5-fluoro PB-22 (Cay-14095) is a synthetic cannabinoid that is an analog of potent 5-fluoropentyl JWH-type cannabimimetics. 5-fluoro PB-22 N-(4-fluoropentyl) isomer differs from 5-fluoro PB-22 by having the fluorine atom at the four, rather than the five, position of the alkyl group. The physiological and...

Lysine-specific demethylase 1 (LSD1) is a protein lysine demethylase that specifically demethylates histone H3 lysine 4 (H3K4), resulting in transcriptional repression. SP-2509 is a reversible inhibitor of LSD1 (IC50 = 13 nM). It has no effect on monoamine oxidases A and B. SP-2509 attenuates the binding of LSD1 to...

AMB (Cay-15488) is an analytical reference standard categorized as a synthetic cannabinoid. This product is intended for research and forensic applications.Formal Name: N-[(1-pentyl-1H-indazol-3-yl)carbonyl]-L-valine, methyl ester. CAS Number: 1890250-13-1. Molecular Formula: C19H27N3O3. Formula Weight: 345.4....

W-18 (Cay-15480) is an analytical reference material categorized as an analgesic. This product is intended for research and forensic applications.Formal Name: 4-chloro-N-[1-[2-(4-nitrophenyl)ethyl]-2-piperidinylidene]-benzenesulfonamide. CAS Number: 93101-02-1. Molecular Formula: C19H20ClN3O4S. Formula Weight:...

Microsomal prostaglandin E2 synthase-1 (mPGES-1) and 5-lipoxygenase (5-LO) are key enzymes in the synthesis of PGE2 (Cay-14010) and leukotrienes (LTs), respectively. PGE2 and LTs are bioactive lipids that contribute to a broad range of pathologies, including inflammation and various forms of cancer. Pirinixic acid...

Desalkylflurazepam (Cay-18484) is an analytical reference material that is structurally categorized as a benzodiazepine. It is an active metabolite of several benzodiazepines, including flurazepam (Cay-18160), flutoprazepam, fludiazepam, midazolam, and quazepam. Desalkylflurazepam inhibits L-type voltage-gated...

W-19 (hydrochloride) (Cay-19484) is an analytical reference material categorized as an analgesic. It is a nitro-reduction metabolite of W-18 (Cay-15480, Cay-19483). This product is intended for research and forensic applications.Formal Name:...

Pyrrolidinophenones (PPPs) are a family of compounds that feature a pyrrolidinyl group affixed to the narcotic cathinone. Many have been identified as components of designer drugs. 2-methyl-alpha-Pyrrolidinopropiophenone (hydrochloride) shares structural features with the stimulant alpha-pyrrolidinopropiophenone and...

Zilpaterol is a beta-adrenergic receptor agonist that putatively through activation of protein kinase A increases protein synthesis in skeletal muscle fibers, as well as reduces lipogenesis and increases lipolysis in adipose tissues. It was approved by the FDA in 2006 as a veterinary food additive for the purpose of...

Detection of the yolk protein Vtg in plasma from juvenile or male fish is a simple and sensitive biomarker for endocrine disrupting chemicals (EDCs) with estrogenic effects in fish. Quantification of Vtg has become an accepted screening test for the estrogenic effects of EDCs in fish. The Vtg (zebrafish) ELISA kit...