- Search results for Cay15740
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10 products were found matching "Cay15740"!
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Item number: Cay15547-50
Hoechst 33342 is a cell-permeable, benzimidazole dye that stains DNA by binding to the minor groove of adenine and thymine-rich sequences. It emits blue fluorescence (excitation 350 nm/emission maximum 461 nm) when bound to double stranded DNA and is useful as a marker of nuclei for cell cycle studies and to...
Keywords: | Bisbenzimide, HOE 33342, NSC 334072, 2'-(4-ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi-1H-benzimidazole,... |
Application: | Blue fluorescent DNA staining, FC, Fluorescence microscopy |
CAS | 875756-97-1 |
MW: | 561.9 D |
From 48.00€
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Item number: Cay15247-10
CID-16020046 is a GPR55 inverse agonist that antagonizes GPR55 constitutive activity with an IC50 value of 15 µM. It inhibits GPR55-mediated ERK1/2 phosphorylation, LPI-induced Ca2+ signaling (IC50 = 0.21 µM in HEK-GPR55 cells), and GPR55-mediated transcription factor activation. It does not affect ERK1/2...
Keywords: | 4-[4,6-dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]-benzoic acid |
Application: | GPR55 inverse agonist |
CAS | 834903-43-4 |
MW: | 425.4 D |
From 48.00€
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Item number: Cay15147-50
Corticotropin-releasing hormone (CRH) secreted from the hypothalamus is the major regulator of pituitary corticotropin-release and consequent glucocorticoid secretion. Antalarmin is a selective, nonpeptide antagonist of the CRH receptor 1 (Ki = 1 nM) that, consequently, reduces the release of corticotropin in...
Keywords: | N-butyl-N-ethyl-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, monohydrochloride |
Application: | CRH receptor 1 antagonist |
CAS | 220953-69-5 |
MW: | 415 D |
From 147.00€
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Item number: Cay15947-10
The bromodomain and extra terminal domain (BET) family of proteins, including BRD2, BRD3, and BRD4, play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes. OTX015 is an...
Keywords: | (-)-OTX015, HY-15743,... |
Application: | BRD2 / BRD3 / BRD4 inhibitor |
CAS | 202590-98-5 |
MW: | 492 D |
From 66.00€
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Item number: Cay15347-10
NS 11021 is an activator of large-conductance Ca2+-activated potassium channels (BKCa/KCa1.1). It is selective for BKCa and is thought to bind directly the alpha subunit. NS 11021 has been shown to relax intracavernous arterial rings and corpus cavernosum strips in vitro and to enhance erectile responses in intact...
Keywords: | N'-[3,5-bis(trifluoromethyl)phenyl]-N-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]-thiourea |
Application: | KCNMA1 activator |
CAS | 956014-19-0 |
MW: | 511.2 D |
From 43.00€
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Item number: Cay15047-10
Wiskott-Aldrich syndrome proteins (WASPs) regulate the actin cytoskeleton by directly interacting with actin in the Arp2/3 complex. As a result, they have essential functions in diverse cellular processes, including phagocytosis, cell motility, and membrane trafficking. Wiskostatin is a cell-permeable, selective...
Keywords: | 3,6-dibromo-alpha-[(dimethylamino)methyl]-9H-carbazole-9-ethanol |
Application: | N-WASP inhibitor |
CAS | 253449-04-6 |
MW: | 426.1 D |
From 92.00€
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Item number: Cay15074-5
JWH 018 (Cay-10900) is a mildly selective agonist of the peripheral cannabinoid (CB2) receptor with Ki values of 9.0 and 2.94 nM for the central cannabinoid (CB1) and CB2 receptors, respectively. JWH 018 benzimidazole analog replaces the indole core of JWH 018 with a benzimidazole core. While the physiological and...
Keywords: | BIM-018, naphthalen-1-yl(1-pentyl-1H-benzo[d]imidazol-2-yl)methanone |
Application: | Analytical reference standard, Synthetic cannabinoid analog |
CAS | 2316839-70-8 |
MW: | 342.4 D |
From 109.00€
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Item number: Cay18745-100
Cefonicid is a second-generation cephalosporin antibiotic. Like other cephalosporins, cefonicid interferes with cell wall biosynthesis in bacteria, leading to lysis of the infectious organism. It is a broad-spectrum antibiotic and has a prolonged serum elimination half-life in animals.Formal Name:...
Keywords: | Monocid,... |
Application: | Antibacterial antibiotic |
CAS | 61270-78-8 |
MW: | 586.5 D |
From 60.00€
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Item number: Cay11745-500
Phyllanthin is a major bioactive lignan component of P. amarus with antioxidative and hepatoprotective properties. It scavenges DPPH radicals with an IC50 value of 7.4 µM and, at 30 µM, has been shown to alleviate carbon tetrachloride-induced lipid peroxidation and cytotoxicity in a human hepatoma HepG2 cell...
Keywords: | NSC 619043, 1,1'-[(2S,3S)-2,3-bis(methoxymethyl)-1,4-butanediyl]bis[3,4-dimethoxy-benzene |
CAS | 10351-88-9 |
MW: | 418.5 D |
From 43.00€
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Item number: Cay16745-100
Horseradish Peroxidase conjugated to Mouse Anti-6Histidine Antibody: Mouse monoclonal anti-6x histidine IgG, clone AD1.1.10 Enzyme: Horseradish Peroxidase Uses: ELISA, microscopy, Western blot detection. Recommended dilution of 1:500-1:10,000. Starting dilution: 1:2,000.Formulation: (Request formulation change),...
Application: | WB |
Host: | Mouse |
488.00€
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